Progressive Lymphangioma
David S. Cassarino, MD, PhD
Key Facts
Terminology
Benign localized proliferation of lymphatic vessels
Clinical Issues
Usually presents on lower extremities but may occur anywhere
Prognosis excellent; local recurrences rare, and metastases do not occur
Microscopic Pathology
Dermal and subcutaneous proliferation of dilated vascular channels
Spaces are often widely dilated superficially but become narrower with deep extension
Endothelial cells may show mild hyperchromasia, but no significant atypia is present
 Low-magnification histologic examination of a progressive lymphangioma shows widely dilated lymphatic spaces in the superficial dermis. |
 Higher magnification shows the widely dilated lymphatic spaces lined by a single layer of small, flattened, bland endothelial cells. |
TERMINOLOGY
Synonyms
Acquired progressive lymphangioma
Benign lymphangioendothelioma
Definitions
Benign localized proliferation of lymphatic vessels
ETIOLOGY/PATHOGENESIS
Unknown
May be related to trauma in some cases
CLINICAL ISSUES
Epidemiology
Age
Middle-aged or older adults
Gender
No predilection
Site
Usually presents on lower extremities but may occur anywhere
Presentation
Slow-growing lesion
Patches or plaques
Stay updated, free articles. Join our Telegram channel
Full access? Get Clinical Tree
