Dermal Clear Cell Mesenchymal Neoplasm David S. Cassarino, MD, PhD Key Facts Terminology Rare, dermal-based clear cell tumor of unknown derivation Clinical Issues Cutaneous nodule Most cases have been reported…

Paraganglioma-like Dermal Melanocytic Tumor David S. Cassarino, MD, PhD Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Paraganglioma-like dermal melanocytic tumor (PDMT) Rare dermal-based, low-grade melanocytic tumor with histologic similarities…

Ectopic Hamartomatous Thymoma Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Rare benign tumor composed of spindle, epithelial, and adipose tissue elements that occurs mainly in lower neck region of…

Hemosiderotic Fibrohistiocytic Lipomatous Lesion Julie C. Fanburg-Smith, MD Aaron Auerbach, MD HEMOSIDEROTIC FIBROHISTIOCYTIC LIPOMATOUS LESION Terminology Benign, probably reactive, lesion that occurs in ankle region of adult females, usually secondary…

Superficial Acral Fibromyxoma Thomas Mentzel, MD Key Facts Terminology Benign fibroblastic neoplasm with predilection for hands and feet, especially nail bed region Clinical Issues Solitary mass involving toe, finger, or…

Superficial Angiomyxoma Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Benign, cutaneous myxoid lesion, associated in some cases with Carney complex Clinical Issues Trunk, head and neck, lower extremities, and…

Juxtaarticular Myxoma Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Benign lesion occurring in region of large joints, with histologic features of myxoma Etiology/Pathogenesis Some associated with trauma or occur…

Intramuscular Myxoma Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Benign soft tissue tumor composed of bland spindle to stellate fibroblasts within abundant extracellular myxoid matrix Clinical Issues Middle-aged adults…

Angiosarcoma of Soft Tissue Thomas Mentzel, MD Key Facts Terminology Malignant mesenchymal neoplasm of cells recapitulating variably morphologic and functional features composed of endothelial cells Clinical Issues Deep soft tissues…

Cutaneous Angiosarcoma Thomas Mentzel, MD Key Facts Terminology Malignant mesenchymal neoplasm of cells variably recapitulating morphologic and functional features composed of endothelial cells Etiology/Pathogenesis Idiopathic (actinic) angiosarcoma Predominantly in actinically…