Paraganglioma-like Dermal Melanocytic Tumor



Paraganglioma-like Dermal Melanocytic Tumor


David S. Cassarino, MD, PhD

Cyril Fisher, MD, DSc, FRCPath









Histologic section shows a diffuse proliferation of clear cells located in the dermis. PDMTs are often a wellcircumscribed but unencapsulated, dermal-based tumor that can extend into the subcutis.






The tumor is composed of closely packed nests of cells with clear or granular cytoplasm and round to oval nuclei with small nucleoli image.


TERMINOLOGY


Abbreviations



  • Paraganglioma-like dermal melanocytic tumor (PDMT)


Definitions



  • Dermal-based low-grade melanocytic tumor with histologic similarities to paraganglioma


CLINICAL ISSUES


Epidemiology



  • Incidence



    • Very rare tumors; only 10 cases reported to date


  • Age



    • Typically occurs in young adults



      • Range: 18-53 years


      • Mean: 35 years


  • Gender



    • More common in females


Site



  • Usually on extremities



    • Mostly lower limb



      • Thigh, knee, lower leg

Jul 9, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Paraganglioma-like Dermal Melanocytic Tumor
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