Congenital Anomalies and Malformation Syndromes Joseph R. Siebert, Ph.D. The study of congenital anomalies continues to be hampered by misunderstandings at a number of levels. In many circles, for example,…
First and Second Trimester Pregnancy Loss Jennifer Pogoriler, M.D., Ph.D. Theonia K. Boyd, M.D.* *Based upon the prior edition chapter by Deborah E. McFadden Pathologic examination of the products of…
Chromosomal Abnormalities Robyn C. Reed, M.D., Ph.D. Michelle M. Dolan, M.D. Raj P. Kapur, M.D., Ph.D. Joseph R. Siebert, Ph.D. Advances in genetic testing have blurred the distinction between the…
Electron Microscopy Gary W. Mierau, Ph.D. Eric P. Wartchow, Ph.D.(c) M. John Hicks, M.D., D.D.S., M.S., Ph.D. Electron microscopy remains an essential tool for today’s pediatric pathologist. Although now increasingly…
Molecular Techniques in Pediatric Pathology Jason A. Jarzembowski, M.D., Ph.D. D. Ashley Hill, M.D. INTRODUCTION Rapid advances in the understanding of the molecular and genetic basis of disease have led…
The Pediatric Autopsy J. Thomas Stocker, M.D. As described by the Autopsy Committee of the College of American Pathologists, the autopsy is “a medical-surgical procedure by a physician for the…
Fine-Needle Aspiration John J. Buchino, M.D. Robert F. Debski, M.D. Fine-needle aspiration (FNA) was first reported in the early 1930s by Martin and Ellis (1) and Stewart (2), but the…
Brain, Spinal Cord, and Meninges Paul E. McKeever TERMS AND ABBREVIATIONS USED IN THIS CHAPTER α-ACT: α-antichymotrypsin macrophage marker; AFP: α-fetoprotein; CADASIL: cerebral autosomal dominant arteriopathy with subcortical infarcts and…
Bone Marrow Steven H. Kroft Alexandra M. Harrington Robert W. McKenna THE BONE MARROW BIOPSY PROCEDURE The bone marrow biopsy is a routine technique in the diagnosis of hematologic disorders,…
Paragangliomas Ernest E. Lack Extra-adrenal paraganglia make up part of the dispersed neuroendocrine system (DNS) having a centripetal and roughly symmetrical distribution with extension from the base of the skull…
