Medical Therapies and Their Effects on Skin Cancer
Fig. 31.1 Keratotic area on the inner ankle of a patient with lupus erythematosus with a 20-year history of immune suppression with numerous medications. The biopsy showed a squamous cell…
Histopathology of Drug Reactions
and Beth Ruben2 (1) Pathology, Miraca Life Sciences, Irving, TX, USA (2) Dermatology and Pathology, University of California, San Francisco, CA, USA Abstract Cutaneous drug reactions can produce a variety…
Cutaneous Drug Reactions in Patients Infected with Human Immunodeficiency Virus
Fig 37.1 Acute retroviral syndrome includes a diffuse maculopapular eruption in 70–80 % patients (Image content provider: CDC Public Health Image Library, donated by Brian Hill, New Zealand.) Despite the…
Cutaneous Reactions to BRAF Inhibitors
Fig. 32.1 Clinical presentation of the maculopapular rash after 2 weeks of therapy with vemurafenib (Courtesy of Rinderknecht et al. (2013)) Fig. 32.2 Histology of the maculopapular rash demonstrates a…
Cutaneous Reactions to Corticosteroids
Fig. 33.1 Severe tinea corporis of the leg due to trichophytun rubrum. It started out much less prominent, but topical and systemic corticosteroid use caused the leg to swell and…
Tyrosine Kinase Medications and the Skin
Fig. 30.1 Acneiform eruption on the face arising shortly after initiation of EGFR inhibitor therapy Treatment of the folliculitis depends on the severity and any associated symptoms. In asymptomatic, relatively…
Collagen Vascular Diseases and Cutaneous Drug Reactions
Fig. 16.1 Annular plaque on the breast of a woman who was on methyldopa. The biopsy was compatible with DLE. The patient was histone positive and improved when the drug…
Drug-Induced Vasculitis
Fig. 8.1 Leukocytoclastic vasculitis secondary to anti-thymocyte globulin in the setting of serum sickness Drugs Associated with Vasculitis Hydralazine Minocycline Isotretinoin Methimazole D-penicillamine Hydralazine Levamisole Penicillin Cephaolosporins Methotrexate Cocaine Propylthiouracil…
Pediatric Drug Eruptions of the Skin
Fig. 38.1 Angioedema in a young boy. Drugs should always be considered as an underlying etiology Histopathology Acute urticaria consists of interstitial edema, dilated venules with endothelial swelling, and minimal…
Acute Generalized Exanthematous Pustulosis
Fig. 26.1 Generalized edematous, erythematous rash preceding pustule presentation. Fig. 26.2 Non-follicular, sterile, pinpoint pustules characteristic of acute generalized exanthematous pustulosis Fig. 26.3 Bullous lesions and lakes of pus In…
