Nucleic Acid Techniques
Chapter 17 Nucleic Acid Techniques Carl T. Wittwer, M.D., Ph.D. and Noriko Kusukawa, Ph.D. Molecular diagnostics requires techniques to detect extremely low concentrations of nucleic acids in a background of…
The Adrenal Cortex
Chapter 54 The Adrenal Cortex Roger L. Bertholf, Ph.D., Ishwarlal Jialal, M.D., Ph.D., F.R.C.Path(London), D.A.B.C.C. and William E. Winter, M.D.* The adrenal cortex and gonads produce steroid hormones. Steroids are…
Clinical Toxicology
Chapter 35 Clinical Toxicology Loralie Langman, Ph.D., F.C.A.C.B., D.A.B.C.C.(C.C.,M.B., T.C.), D.A.B.F.T., Laura Bechtel, Ph.D., D.A.B.C.C. and Christopher P. Holstege, M.D. Toxicology is a broad, multidisciplinary science whose goal is to…
Hemostasis
Chapter 59 Hemostasis Russell A. Higgins, M.D., Steve Kitchen, Ph.D. and John D. Olson, M.D., Ph.D. Hemostasis is the mechanism by which animals with a vascular system protect themselves from…
Quality Management
Chapter 8 Quality Management George G. Klee, M.D., Ph.D. and James O. Westgard, Ph.D. The principles of quality management, assurance, and control have become the foundation by which clinical laboratories…
Hemoglobin, Iron, and Bilirubin
Chapter 32 Hemoglobin, Iron, and Bilirubin Trefor Higgins, M.Sc., John H. Eckfeldt, M.D., Ph.D., James C. Barton, M.D. and Basil T. Doumas, Ph.D.* Hemoglobin (Hb), iron (Fe), and bilirubin are…
Principles of Basic Techniques and Laboratory Safety
Chapter 9 Principles of Basic Techniques and Laboratory Safety Stanley F. Lo, Ph.D., D.A.B.C.C., F.A.C.B.* To reliably perform qualitative and quantitative analyses on body fluids and tissue, the clinical laboratorian…
Vitamins and Trace Elements
Chapter 31 Vitamins and Trace Elements Alan Shenkin, Ph.D., and Norman B. Roberts, Ph.D., C.Chem.* Adequate supplies of vitamins and trace elements are critical in maintaining the health and development…
Serum Enzymes
Chapter 22 Serum Enzymes Mauro Panteghini, M.D. and Renze Bais, Ph.D., A.R.C.P.A. Measurements of enzymes are used in medicine in two major ways. Enzymes are measured in serum and other…
Optical Techniques
Chapter 10 Optical Techniques Larry J. Kricka, D.Phil., F.A.C.B., C.Chem., F.R.S.C., F.R.C.Path. and Jason Y. Park, M.D., Ph.D., F.C.A.P.* Many determinations made in the clinical laboratory are based on measurements…
