Cell type Advantages Disadvantages MNC Multipotent and autologous Limited expansion and high cell heterogeneity Skeletal myoblast Autologous, easy isolation and expansion Arrhythmogenic and lack of electromechanical coupling MSC Multipotent, autologous,…
Fig. 17.1 Cross-section of the amniotic sac stained with hematoxylin–eosin. On the left hand, subdivisions of amniotic sac: amnion, intermediate layer, and chorion (magnification ×40). On the right hand, subsections…
Fig. 15.1 Role of the placenta in the ontogeny of the human hematopoietic system. The sequential role of various intra-embryonic and extra-embryonic tissues in hematopoiesis is represented We have updated…
Indication Testing condition Result Reference In vitro In vivo In vitro In vivo To verify the capability of hAFSCs of osteogenic differentiation forming tissue-engineered bone Printed hAFSC-alginate/collagen scaffold are differentiated…
Fig. 11.1 AFS for prenatal and perinatal intervention. AFS collected from the amniotic fluid are expanded and either directly administered, or incorporated into scaffolds for tissue engineering, and subsequently transplanted,…
, Joseph M. Scandura1, Shahin Rafii1 and Venkat R. Pulijaal2 (1) Department of Medicine, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10064, USA (2) Pathology and Laboratory Medicine, Weill Cornell Medical College, 1300…
Fig. 32.1 The average timeline for patent filing In the next step, the non-provisional patent or patent corporation treaty (PCT) application is filed. Within 3 months of a PCT application,…
Fig. 4.1 Comparison of acute and chronic graft-versus-host disease (GVHD) 3.1 Pathophysiology of GVHD Physiologic causes and effects of acute GVHD have been well characterized (Fig. 4.2) [18, 21, 24]….
MSC population Pancreatic differentiation protocol Analysis of markers expression Functional assays References WJ-MSCs 4 steps: Step 1 with neuronal conditioned medium (NCM) for 7 days Step 2 H-DMEM/F12 (25 mM…
Fig. 16.1 Photomicrograph of a typical articular cartilage stained by hematoxylin and eosin staining. Articular cartilage can be subdivided into different zones from the cartilage surface to subchondral bone. In…
