Summary

Jul 12, 2017 by in BIOCHEMISTRY Comments Off on Summary

Section 5.1     Drug molecules often have one or more acidic and/or basic functional groups. The charge state of these groups varies with pH and affects a range of properties, including drug…

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Summary

Jul 12, 2017 by in BIOCHEMISTRY Comments Off on Summary

Section 4.1     Rotations about single bonds in molecules result in different interconverting shapes or conformations. Specific conformations (also called conformers) may be different in shape and energy but their interconversion does…

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Summary

Jul 12, 2017 by in BIOCHEMISTRY Comments Off on Summary

Section 2.1     A variety of non-covalent interactions can be involved in the recognition of a drug substance by its biological target. Section 2.2     A binding event between drug and target molecule can…

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The quantum mechanical description of nature

Jul 12, 2017 by in BIOCHEMISTRY Comments Off on The quantum mechanical description of nature

The quantum mechanical description of nature PREVIEW OF IMPORTANT CONCEPTS We can expect to observe quantum mechanical effects and the insufficiency of a classical mechanical description when at least one…

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Statistical mechanics

Jul 12, 2017 by in BIOCHEMISTRY Comments Off on Statistical mechanics

Statistical mechanics PREVIEW OF IMPORTANT CONCEPTS The objective of this chapter is to draw a connection between molecules and macroscopically measureable thermodynamic properties. Conventional matter is made up of atoms…

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Model quantum systems

Jul 12, 2017 by in BIOCHEMISTRY Comments Off on Model quantum systems

Model quantum systems PREVIEW OF IMPORTANT CONCEPTS Confinement in one dimension requires one quantum number to determine the energy. Confinement in three dimensions requires three quantum numbers. Confinement leads to…

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Solutions and mixtures: Nonelectrolytes

Jul 12, 2017 by in BIOCHEMISTRY Comments Off on Solutions and mixtures: Nonelectrolytes

Solutions and mixtures: Nonelectrolytes PREVIEW OF IMPORTANT CONCEPTS A mixture is a combination of two or more substances in any proportion. In a solution, the solvent is clearly defined because…

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