Cell Lines and Organism A number of different cell lines have been used to propagate C. trachomatis, including McCoy, HeLa 229, and BHK-21 (clone 13). According to a recent study,…
POLYENES Amphotericin B (AmB), natamycin, and nystatin are the currently available polyenes, although differing safety profiles have limited natamycin and nystatin to topical use (2). Polyenes possess a large lactone…
The cytoplasmic membrane in each group of bacteria is a semipermeable membrane that regulates molecular flow, in turn determining pH (143,148,149), osmotic pressures (150), and availability of essential substances. The…
Resistance to β-lactam antibiotics can occur by one of three major mechanisms: inactivating enzymes (BLAs), low-affinity penicillin-binding proteins (PBPs), or decreased permeability. BLA is by far the most common mechanism…
FIGURE 1 | The main steps of translation. FIGURE 2 | Crystal structure of three tRNA molecules interacting with an mRNA molecule and the 16s rRNA in the 30S ribosome…
Figure 1 Schematic showing the mixed dispensability present in the biosynthetic pathways of many Gram-positive cell-wall surface polymers that are assembled on a bactoprenol carrier lipid and act as virulence…
Figure 1 Mechanisms of antibiotic resistance. Panel a, for inhibiting bacterial growth, an antibiotic (1), requires traverse the cellular envelopes either by specific transporters (2) or by diffusion through the…
