Papillary Endothelial Hyperplasia (Masson Tumor) Amitabh Srivastava, MD Key Facts Terminology Benign, reactive, intravascular papillary endothelial proliferation Clinical Issues Wide site distribution; located in deep dermis or subcutaneous tissue Macroscopic…
Angiokeratoma Steven D. Billings, MD Key Facts Terminology Ectatic superficial dermal blood vessels associated with reactive epidermal hyperplasia Clinical Issues Solitary and multiple angiokeratomas Angiokeratoma of Fordyce Angiokeratoma of Mibelli…
Capillary, Venous, and Cavernous Hemangiomas Amitabh Srivastava, MD Key Facts Terminology Benign vascular tumors composed of blood vessels lined by plump to flattened endothelial cells with no atypia Etiology/Pathogenesis May…
Verrucous Hemangioma Steven D. Billings, MD David Cassarino, MD, PhD Key Facts Clinical Issues Presents in children Dark blue nodule Surface has warty appearance Most common on the extremities Microscopic…
Hobnail (Targetoid Hemosiderotic) Hemangioma David Cassarino, MD, PhD Key Facts Terminology Targetoid hemosiderotic hemangioma Benign vascular proliferation, typically wedge-shaped, showing intravascular papillae and hobnailed endothelial cells Etiology/Pathogenesis Postulated to represent…
Epithelioid Sarcoma Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Malignant mesenchymal tumor resembling carcinoma or granuloma Classical and proximal aggressive forms Etiology/Pathogenesis Some have abnormalities of chromosome 22q Clinical…
Spindle Cell Hemangioma Steven D. Billings, MD Key Facts Terminology Formerly called spindle cell hemangioendothelioma Clinical Issues Subcutaneous mass Usually acral location Sometimes multifocal Local recurrence in 50-60% of cases…
Angiolymphoid Hyperplasia with Eosinophilia Lester D. R. Thompson, MD Key Facts Terminology Benign vascular tumor with well-formed, immature blood vessels associated with prominent inflammatory component, rich in eosinophils Clinical Issues…
Glomeruloid Hemangioma David Cassarino, MD, PhD Key Facts Terminology Glomeruloid angioma Etiology/Pathogenesis Association with polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes (POEMS) or multicentric Castleman syndrome in most cases Clinical Issues…
Tufted Angioma David Cassarino, MD, PhD Key Facts Terminology Acquired tufted angioma (ATA) Angioblastoma (of Nakagawa) Multiple cannonball-like cellular collections of small vessels in dermis Clinical Issues Children and young…
