Principles of Immunochemical Techniques
Chapter 16 Principles of Immunochemical Techniques Larry J. Kricka, D. Phil., F.A.C.B., C. Chem., F.R.S.C., F.R.C.Path. and Jason Y. Park, M.D., Ph.D., F.A.C.P.* Immunochemical reactions form the basis of a…
Establishment and Use of Reference Values
Chapter 5 Establishment and Use of Reference Values Gary L. Horowitz, M.D.* Medicine is an art and a science in the service of fellow human beings. To improve the health…
Hematopoietic Malignancies
Chapter 44 Hematopoietic Malignancies Kojo S.J. Elenitoba-Johnson, M.D. The hematologic malignancies include leukemias, lymphomas, myeloproliferative disorders, and plasma cell neoplasia. The leukemias are primarily bone marrow and peripheral blood–based processes,…
Amino Acids, Peptides, and Proteins
Chapter 21 Amino Acids, Peptides, and Proteins Glen L. Hortin, M.D., Ph.D* Amino acids, peptides, and proteins are crucial for virtually all biological processes. Amino acids have diverse roles in…
Pituitary Function and Pathophysiology
Chapter 53 Pituitary Function and Pathophysiology William E. Winter, M.D., Ishwarlal Jialal, M.D., Ph.D., F.R.C.Path(London), D.A.B.C.C., Mary Lee Vance, M.D. and Roger L. Bertholf, Ph.D.* The pituitary gland (also called…
Pharmacogenetics
Chapter 43 Pharmacogenetics Gwendolyn A. McMillin, Ph.D., D.A.B.C.C.(C.C., T.C.)* The term pharmacogenetics comes from merging the names of pharmacology (the study of drugs, particularly drug handling and drug response) and…
Diabetes Mellitus
Chapter 46 Diabetes Mellitus David B. Sacks, M.B., Ch.B., F.R.C.Path. Diabetes mellitus is a group of metabolic disorders of carbohydrate metabolism in which glucose is underused, producing hyperglycemia. Some patients…
Reproductive Endocrinology and Related Disorders
Chapter 56 Reproductive Endocrinology and Related Disorders T. Scott Isbell, Ph.D., Emily Jungheim, M.D. and Ann M. Gronowski, Ph.D.* Reproductive endocrinology encompasses the hormones of the hypothalamic-pituitary-gonadal axis, as well…
Microfabrication and Microfluidics and Their Application to Clinical Diagnostics
Chapter 18 Microfabrication and Microfluidics and Their Application to Clinical Diagnostics Lindsay A.L. Bazydlo, Ph.D. and James P. Landers, Ph.D. Background The first miniaturized analytical device with some degree of…
Inherited Diseases
Chapter 40 Inherited Diseases Cindy L. Vnencak-Jones, Ph.D., F.A.C.M.G. Since the first description of the use of the polymerase chain reaction (PCR) for the diagnosis of sickle cell anemia in…
