Inborn Errors of Metabolism
Inborn Errors of Metabolism Peter Pytel, M.D. Selene Koo, M.D., Ph.D. Darrel Waggoner, M.D. INTRODUCTION Over 100 years ago, in 1908, Archibald Garrod delivered his four Croonian Lectures during which…
Congenital Anomalies and Malformation Syndromes
Congenital Anomalies and Malformation Syndromes Joseph R. Siebert, Ph.D. The study of congenital anomalies continues to be hampered by misunderstandings at a number of levels. In many circles, for example,…
First and Second Trimester Pregnancy Loss
First and Second Trimester Pregnancy Loss Jennifer Pogoriler, M.D., Ph.D. Theonia K. Boyd, M.D.* *Based upon the prior edition chapter by Deborah E. McFadden Pathologic examination of the products of…
Chromosomal Abnormalities
Chromosomal Abnormalities Robyn C. Reed, M.D., Ph.D. Michelle M. Dolan, M.D. Raj P. Kapur, M.D., Ph.D. Joseph R. Siebert, Ph.D. Advances in genetic testing have blurred the distinction between the…
Electron Microscopy
Electron Microscopy Gary W. Mierau, Ph.D. Eric P. Wartchow, Ph.D.(c) M. John Hicks, M.D., D.D.S., M.S., Ph.D. Electron microscopy remains an essential tool for today’s pediatric pathologist. Although now increasingly…
Molecular Techniques in Pediatric Pathology
Molecular Techniques in Pediatric Pathology Jason A. Jarzembowski, M.D., Ph.D. D. Ashley Hill, M.D. INTRODUCTION Rapid advances in the understanding of the molecular and genetic basis of disease have led…
The Pediatric Autopsy
The Pediatric Autopsy J. Thomas Stocker, M.D. As described by the Autopsy Committee of the College of American Pathologists, the autopsy is “a medical-surgical procedure by a physician for the…
Fine-Needle Aspiration
Fine-Needle Aspiration John J. Buchino, M.D. Robert F. Debski, M.D. Fine-needle aspiration (FNA) was first reported in the early 1930s by Martin and Ellis (1) and Stewart (2), but the…
