Fig. 14.1 Comparison of desmoplastic nevus (left) and desmoplastic melanoma (right). Desmoplastic nevus, as some Spitz nevi do, may show many cells expressing HMB45 antigen in the dermis; however, anti-Ki67…
Fig. 8.1 Nevoid malignant melanoma. (a) The lesion displays circumscription, but cellular crowding (×10). (b) Note nuclear pleomorphism. Mitotic figures are scattered in the lesion including its base (×40). (c)…
Fig. 4.1 Distinction between nevus and melanoma. (a) HMB45 labels the intraepidermal and upper dermal components of this large compound nevus. In contrast (b) melanoma cells show strong, but patchy…
Fig. 7.1 Comparison of halo nevus (a) and superficial spreading melanoma with focal regression (b). Low magnification; exophytic, symmetrical melanocytic lesion with a dense, regularly distributed, lichenoid infiltrate that obscures…
Fig. 6.1 Compound Spitz nevus: (a and b) note the regular elongation of rete ridges and the wedge-shape of the lesion in the dermis. (c) Large epithelioid cells in the…
© Springer Science+Business Media New York 2015Christopher R. Shea, Jon A. Reed and Victor G. Prieto (eds.)Pathology of Challenging Melanocytic Neoplasms10.1007/978-1-4939-1444-9_5 5. Applications of Additional Techniques to Melanocytic Pathology Victor G. Prieto1 , Christopher R. Shea2 and Jon A. Reed3 (1) MD Anderson…
Fig. 1.1 Microscopic evaluation of peripheral margins. (a) Melanoma in situ involving the inked peripheral margin of a specimen (×20). (b) Atypical nevus excised with a margin of un-involved skin…
