Monocytes, Histiocytes, and Storage Disorders Diane C. Farhi This section discusses reactive changes in monocytes and histiocytes, as well as constitutional and acquired storage disorders, which are predominantly manifested as…
Erythrocytes Carolyn Chiling Chai Red blood cells (RBCs) decrease in size as they mature and lose the nucleus. The cytoplasm turns from blue to pink-orange as they acquire hemoglobin (Hb)….
Neutrophils Diane C. Farhi This section focuses on acquired and reactive neutrophil changes in the peripheral blood and bone marrow. Constitutional disorders of neutrophils are discussed in Chapter 4. Clonal…
Eosinophils and Basophils Diane C. Farhi This section discusses acquired and reactive changes in eosinophils and basophils in the peripheral blood and bone marrow. Constitutional disorders of eosinophils and basophils…
Constitutional Hematopoietic Disorders Diane C. Farhi The constitutional hematopoietic disorders are a heterogenous group with regard to clinical presentation and pathology. Genetically, these disorders may be inherited or arise de…
Extramedullary Hematopoiesis Diane C. Farhi Extramedullary hematopoiesis (EMH) is found in numerous settings (Table 3.1). Common underlying causes include increased hematopoiesis, as seen in constitutional and acquired hematopoietic disorders, and…
Bone Marrow Procedure, Examination, and Reporting Carolyn Chiling Chai The osseous portion of the human bone consists of hematopoietic cells, fat cells, and supporting connective tissue separated by irregular bony…
Bone Marrow Structure, Morphology, and Hematopoiesis Thuy-Lieu Thi Vo Diane C. Farhi BONE MARROW STRUCTURE Bone marrow is a red, soft, semisolid, gelatinous, mesenchymal-derived tissue occupying the medullary cavities of…
