Prophylaxis of Atherosclerotic Cardiovascular Disease

Apr 8, 2017 by in PHARMACY Comments Off on Prophylaxis of Atherosclerotic Cardiovascular Disease

Figure 42.1 Basic structure of plasma lipoproteins.  Apolipoproteins All lipoproteins have one or more apolipoprotein molecules embedded in their shell (see Fig. 42.1). Apolipoproteins, which constitute the protein component of lipoproteins,…

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Antiviral Agents II

Apr 8, 2017 by in PHARMACY Comments Off on Antiviral Agents II

Figure 79.1 Structure of the human immunodeficiency virus. Note that HIV has two single strands of RNA and that each strand is associated with a molecule of reverse transcriptase. gp41, glycoprotein 41;…

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Drugs for Hypertension

Apr 8, 2017 by in PHARMACY Comments Off on Drugs for Hypertension

Diuretics Hydrochlorothiazide Spironolactone Beta-Adrenergic Blocker Metoprolol Inhibitors of the Renin-Angiotensin-Aldosterone System Captopril (angiotensin-converting enzyme inhibitor) Losartan (angiotensin II receptor blocker) Aliskiren (direct renin inhibitor) Eplerenone (aldosterone antagonist) Calcium Channel Blockers…

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Estrogens and Progestins

Apr 8, 2017 by in PHARMACY Comments Off on Estrogens and Progestins

Figure 48.1 The menstrual cycle: anatomic and hormonal changes. FSH, follicle-stimulating hormone; LH, luteinizing hormone.  Ovarian and Uterine Events The menstrual cycle consists of a coordinated series of ovarian and uterine events….

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Antihistamines

Apr 8, 2017 by in PHARMACY Comments Off on Antihistamines

Figure 54.1 Release of histamine by allergen-antibody interaction. (IgE, immunoglobulin E.)  Nonallergic Release Several agents (certain drugs, radiocontrast media, plasma expanders) can act directly on mast cells to trigger histamine release. With…

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Drugs for Weight Loss

Apr 8, 2017 by in PHARMACY Comments Off on Drugs for Weight Loss

Figure 66.1 Body mass index calculation.  Figure 66.2 Adult weight classification based on body mass index (BMI). (Adapted from National Heart, Lung, and Blood Institute Body Mass Index Table, 2012. Complete table available…

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Miscellaneous Antibacterial Drugs

Apr 8, 2017 by in PHARMACY Comments Off on Miscellaneous Antibacterial Drugs

Fluoroquinolone Ciprofloxacin Cyclic Lipopeptide Daptomycin Mechanism of Action Ciprofloxacin inhibits two bacterial enzymes: DNA gyrase and topoisomerase IV. Both are needed for DNA replication and cell division. DNA gyrase converts…

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Drug Therapy of Rheumatoid Arthritis

Apr 8, 2017 by in PHARMACY Comments Off on Drug Therapy of Rheumatoid Arthritis

Figure 57.1 Progressive joint degeneration in rheumatoid arthritis. A, Healthy joint. B, Inflammation of synovial membrane. C, Onset of pannus formation and cartilage erosion. D, Pannus formation progresses, and cartilage deteriorates further….

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Review of the Immune System

Apr 8, 2017 by in PHARMACY Comments Off on Review of the Immune System

Figure 52.1 Maturation of blood cells. With the exception of platelets and erythrocytes, all of the mature blood cells shown participate in immune responses. However, only cells of lymphoid origin (cytolytic T…

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