Massive Localized Lymphedema in Morbid Obesity Steven D. Billings, MD Key Facts Clinical Issues Seen in morbidly obese patients (> 300 lbs) Macroscopic Features Overlying skin has “peau d’orange” appearance…
Lymphangioma and Lymphangiomatosis David S. Cassarino, MD, PhD Key Facts Terminology Lymphangioma circumscriptum (superficial lymphangioma) (LAC) Lymphangiomatosis (systemic angiomatosis) (LAS) Cystic lymphangioma (cystic hygroma) Deep lymphangioma (cavernous lymphangioma) Etiology/Pathogenesis Most…
Progressive Lymphangioma David S. Cassarino, MD, PhD Key Facts Terminology Benign localized proliferation of lymphatic vessels Clinical Issues Usually presents on lower extremities but may occur anywhere Prognosis excellent; local…
Angiomatosis David R. Lucas, MD Key Facts Terminology Diffuse, benign, vascular lesion of soft tissue affecting large segments of body or multiple tissue planes in contiguous fashion Clinical Issues Most…
Epithelioid Hemangioma Steven D. Billings, MD Key Facts Terminology Angiolymphoid hyperplasia with eosinophilia, histiocytoid hemangioma Benign vascular tumor with epithelioid endothelial cells, usually accompanied by lymphoid aggregates and eosinophils Clinical…
Acquired Tufted Angioma David S. Cassarino, MD, PhD Key Facts Terminology Acquired tufted angioma (ATA) Angioblastoma (of Nakagawa) Multiple cannonball-like cellular collections of small vessels in dermis Clinical Issues Children…
Spindle Cell Hemangioma Steven D. Billings, MD Key Facts Terminology Formerly called spindle cell hemangioendothelioma Clinical Issues Subcutaneous mass Usually acral location Sometimes multifocal Associated with Mafucci syndrome in some…
Capillary, Venous, and Cavernous Hemangiomas Amitabh Srivastava, MD Key Facts Terminology Benign vascular tumors composed of blood vessels lined by plump to flattened endothelial cells with no atypia Etiology/Pathogenesis May…
Leiomyosarcoma Elizabeth A. Montgomery, MD Key Facts Terminology Malignant neoplasm composed of cells exhibiting smooth muscle differentiation Etiology/Pathogenesis Epstein-Barr virus-associated in immunosuppressed patients Clinical Issues Retroperitoneal and inferior vena cava…
Papillary Endothelial Hyperplasia Amitabh Srivastava, MD Key Facts Terminology Benign, reactive, intravascular papillary endothelial proliferation Clinical Issues Wide site distribution; located in deep dermis or subcutaneous tissue Macroscopic Features Small,…
