Acute Thymic Involution

Jul 8, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Acute Thymic Involution

Acute Thymic Involution Jessica M. Comstock, MD Key Facts Terminology Incidental thymic involution caused by endogenous steroid release in response to various stressful situations Etiology/Pathogenesis Numerous stressors including infection, chronic…

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Transient Erythroblastopenia of Childhood

Jul 8, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Transient Erythroblastopenia of Childhood

Transient Erythroblastopenia of Childhood Kathryn Foucar, MD Key Facts Terminology Self-limited red cell aplasia characterized by Normocytic/normochromic anemia with reticulocytopenia Decreased erythroid lineage in bone marrow (red cell aplasia) Etiology/Pathogenesis…

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Mycobacterial Infection

Jul 8, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Mycobacterial Infection

Mycobacterial Infection Tariq Muzzafar, MBBS Key Facts Clinical Issues High index of suspicion essential for diagnosis Definitive diagnosis by histology and culture of LN Molecular methods enable quicker identification of…

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Toxoplasma Lymphadenitis

Jul 8, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Toxoplasma Lymphadenitis

Toxoplasma Lymphadenitis Carlos E. Bueso-Ramos, MD, PhD Key Facts Etiology/Pathogenesis Toxoplasma gondii is parasitic protozoan Cat is definitive host for sexual stage of reproduction Trophozoite-containing oocysts are eliminated in feces…

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Chronic Granulomatous Lymphadenitis

Jul 8, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Chronic Granulomatous Lymphadenitis

Chronic Granulomatous Lymphadenitis C. Cameron Yin, MD, PhD Key Facts Terminology Granulomatous inflammation is specific type of inflammatory response Characterized by accumulation of modified macrophages (epithelioid cells) Initiated by infectious…

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Rosai-Dorfman Disease

Jul 8, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Rosai-Dorfman Disease

Rosai-Dorfman Disease L. Jeffrey Medeiros, MD Roberto N. Miranda, MD Key Facts Terminology Rosai-Dorfman disease (RDD) and sinus histiocytosis with massive lymphadenopathy are equivalent terms Etiology/Pathogenesis Unknown; histologic features are…

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Kimura Disease

Jul 8, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Kimura Disease

Kimura Disease C. Cameron Yin, MD, PhD Key Facts Terminology Chronic inflammatory disease that affects subcutaneous tissue and regional lymph nodes Etiology/Pathogenesis Unknown; infectious cause suspected Clinical Issues Mainly in…

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Infectious Mononucleosis Lymphadenitis

Jul 8, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Infectious Mononucleosis Lymphadenitis

Infectious Mononucleosis Lymphadenitis Pei Lin, MD Key Facts Etiology/Pathogenesis Epstein-Barr virus infection Clinical Issues Fever Pharyngitis Lymphadenopathy Microscopic Pathology Follicular and interfollicular hyperplasia Range of cells from small mature forms…

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