Transient Erythroblastopenia of Childhood



Transient Erythroblastopenia of Childhood


Kathryn Foucar, MD









Peripheral blood smear shows a profound normocytic/normochromic anemia without polychromasia. There is minimal, if any, anisopoikilocytosis of RBCs.






Bone marrow aspirate smear illustrates a marked decrease in the erythroid lineage with only rare erythroblasts image and no maturing forms. Granulocytic lineage is normal.


TERMINOLOGY



Synonyms



  • Transient red cell aplasia



ETIOLOGY/PATHOGENESIS


Multifactorial Causes



  • Unclear; usually no causative factor identified


  • Underlying viral infection or immune aberration postulated but not consistently documented


  • Rare reports in siblings

Jul 8, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Transient Erythroblastopenia of Childhood
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