Fig. 32.1 Clinical presentation of the maculopapular rash after 2 weeks of therapy with vemurafenib (Courtesy of Rinderknecht et al. (2013)) Fig. 32.2 Histology of the maculopapular rash demonstrates a…

Fig. 33.1 Severe tinea corporis of the leg due to trichophytun rubrum. It started out much less prominent, but topical and systemic corticosteroid use caused the leg to swell and…

Fig. 30.1 Acneiform eruption on the face arising shortly after initiation of EGFR inhibitor therapy Treatment of the folliculitis depends on the severity and any associated symptoms. In asymptomatic, relatively…

Fig. 8.1 Leukocytoclastic vasculitis secondary to anti-thymocyte globulin in the setting of serum sickness Drugs Associated with Vasculitis Hydralazine Minocycline Isotretinoin Methimazole D-penicillamine Hydralazine Levamisole Penicillin Cephaolosporins Methotrexate Cocaine Propylthiouracil…

Fig. 16.1 Annular plaque on the breast of a woman who was on methyldopa. The biopsy was compatible with DLE. The patient was histone positive and improved when the drug…

Fig. 38.1 Angioedema in a young boy. Drugs should always be considered as an underlying etiology Histopathology Acute urticaria consists of interstitial edema, dilated venules with endothelial swelling, and minimal…

Fig. 26.1 Generalized edematous, erythematous rash preceding pustule presentation. Fig. 26.2 Non-follicular, sterile, pinpoint pustules characteristic of acute generalized exanthematous pustulosis Fig. 26.3 Bullous lesions and lakes of pus In…

Fig. 24.1 Dusky red discoloration with trunkal involvement that is often seen early in TEN. Early desqumation is starting over lower abdominal panniculus. Reaction was to Bactrim Early cutaneous findings…

Fig. 34.1 Severe dryness and fissuring of lips and nose in a patient on isotretinoin Fig. 34.2 Xerotic skin with reticulate fissuring seen in asteatotic dermatitis over the ankle in…

  Phototoxicity Photoallergy Incidence High Low Amount of agent required for photosensitivity Large Small Onset after exposure to photosensitizer and light Minutes to hours 24 h or more Occurs after…