Inhalation Drug Delivery
1.1 Introduction The lung offers a unique and challenging route for drug delivery for the treatment of local respiratory and systemic diseases. Advances in drug formulation and inhalation device design…
1.1 Introduction The lung offers a unique and challenging route for drug delivery for the treatment of local respiratory and systemic diseases. Advances in drug formulation and inhalation device design…
7.1 Proteins and Peptides for Inhalation Proteins are polymers consisting of amino acids covalently linked by peptide bonds. Peptides are small proteins composed of up to a few dozen amino…
Fig. 22.1 Proximal nail fold epithelium (200×) Fig. 22.2 Nail plate with nail bed epithelium (1000×) Fig. 22.3 Nail plate with nail bed epithelium (400×) Fig. 22.4 Nail matrix lining…
Fig. 17.1 Adult with multiple FDE due to a Cephalosporin Fig. 17.2 Recurrent localized FDE. Hyperpigmented patch with surrounding violaceous erythema Fig. 17.3 Bulla formation in localized FDE The first…
Fig. 29.1 Xerosis: significant dryness of the skin of the foot Fig. 29.2 Xerosis: fissures of the hands Dry skin can be attributed to abnormal keratinocyte differentiation, which leads to…
Condition Appearance Location Histopathology Associations Sweet’s syndrome Papules, plaques, nodules Head, neck, upper extremity Massive papillary dermal edema, nodular and diffuse neutrophilic infiltration with karyorrhexis Fever, leukocytosis, arthralgias Pyoderma gangrenosum…
Warfarin-induced skin necrosis Heparin-induced skin necrosis Heparin delayed-type hypersensitivity Incidence 0.01–0.1 % UFH: <3 % LMWH: <0.1 % 7.5 % Onset 90 % day 3–6 Almost all by day…
Fig. 31.1 Keratotic area on the inner ankle of a patient with lupus erythematosus with a 20-year history of immune suppression with numerous medications. The biopsy showed a squamous cell…
and Beth Ruben2 (1) Pathology, Miraca Life Sciences, Irving, TX, USA (2) Dermatology and Pathology, University of California, San Francisco, CA, USA Abstract Cutaneous drug reactions can produce a variety…
Fig 37.1 Acute retroviral syndrome includes a diffuse maculopapular eruption in 70–80 % patients (Image content provider: CDC Public Health Image Library, donated by Brian Hill, New Zealand.) Despite the…