Spiradenoma Steven D. Billings, MD Key Facts Clinical Issues Upper 1/2 of body most commonly involved Dermal mass/nodule, < 2 cm in size Often tender or painful lesion Microscopic Pathology…

Cylindroma Steven D. Billings, MD Key Facts Etiology/Pathogenesis Familial cases associated with Brooke-Spiegler syndrome Clinical Issues Marked female predominance (F:M = 9:1) 90% present on head and neck Microscopic Pathology…

Hidradenocarcinoma Christine J. Ko, MD David Cassarino, MD, PhD Key Facts Terminology Malignant acrospiroma, malignant hidradenoma Malignant adnexal tumor arising from, or showing areas similar to, a hidradenoma Clinical Issues…

Porocarcinoma David Cassarino, MD, PhD Key Facts Etiology/Pathogenesis May arise from malignant transformation of longstanding poroma Clinical Issues Rare tumors; approximately 200 cases reported Usually occur in elderly patients Acral…

Poroma and Dermal Duct Tumor David Cassarino, MD, PhD Key Facts Terminology Eccrine poroma Apocrine poroma Hidroacanthoma simplex (intraepidermal poroma, syringoacanthoma) Acrospiroma (older term, includes poroma and hidradenoma) Benign adnexal…

Hidradenoma Christine J. Ko, MD Key Facts Clinical Issues Solitary dermal nodule Microscopic Pathology May be primarily composed of solid areas, cystic areas, or both Classically does not connect to…

Syringocystadenoma Papilliferum Steven D. Billings, MD Key Facts Clinical Issues Approximately 1/2 present at birth or childhood Scalp most common location, followed by face Often associated with nevus sebaceus (present…

Hidradenoma Papilliferum Senait W. Dyson, MD David Cassarino, MD, PhD Key Facts Terminology Well-circumscribed adenoma with apocrine differentiation Clinical Issues Rare, benign tumor Vulvar or perianal area, predominately in women…

Sebaceous Carcinoma David Cassarino, MD, PhD Key Facts Terminology Adnexal carcinoma that often lacks clear cell features in poorly differentiated cases Etiology/Pathogenesis Strong association with MTS if patients have multiple…

Apocrine Tubular Adenoma Elsa F. Velazquez, MD David Cassarino, MD, PhD Key Facts Clinical Issues Scalp Nodule measuring < 2 cm Microscopic Pathology Intradermal tumor Sometimes arises in association with…