Vascular Hamartomas Steven D. Billings, MD Key Facts Clinical Issues Port-wine stain Usually involves head and neck Sturge-Weber syndrome Port-wine stain involving ophthalmic branch of trigeminal nerve Klippel-Trenaunay-Weber syndrome Port-wine…
Cutaneous Malignant Fibrous Histiocytoma/Pleomorphic Sarcoma Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Anaplastic sarcoma composed of pleomorphic spindle and polygonal cells No other definable differentiation, other than fibroblastic or…
Low-Grade Fibromyxoid Sarcoma (Evans Tumor) Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Malignant fibroblastic neoplasm composed of bland spindle cells in collagenous matrix, often with prominent collagenous nodules Characterized…
Dermatofibrosarcoma Protuberans David Cassarino, MD, PhD Key Facts Terminology Low-grade malignant spindle cell tumor of skin characteristically showing prominent storiforming Variant: Bednar tumor (pigmented DFSP) Clinical Issues Typically occurs in…
Fibrosarcoma Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Soft tissue sarcoma composed of fibroblasts Lacks features of specific types of fibrosarcoma Etiology/Pathogenesis Exceptionally rare if strictly defined Microscopic Pathology…
Angiomatoid Fibrous Histiocytoma Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Rare neoplasm of intermediate biologic potential Most often arises in extremities of children and young adults Histologically often confused…
Plexiform Fibrohistiocytic Tumor Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Fibrohistiocytic tumor of intermediate malignant potential Microscopic Pathology Tumor based at dermal-subcutaneous junction Infiltrative, plexiform, or multinodular growth pattern…
Distinctive Dermal Clear Cell Mesenchymal Tumor David Cassarino, MD, PhD Key Facts Terminology Rare, dermal-based clear cell tumor of unknown derivation Clinical Issues Cutaneous nodule Most cases have been reported…
Superficial Acral Fibromyxoma Thomas Mentzel, MD Key Facts Terminology Benign fibroblastic neoplasm with predilection for hands and feet Clinical Issues Rare tumor Dermal &/or subcutaneous neoplasm Mainly adults Biologically benign…
Cutaneous Myxoma and Angiomyxoma Steven D. Billings, MD Key Facts Etiology/Pathogenesis May be associated with Carney complex (also known as NAME and LAMB syndromes) If patient has multiple cutaneous myxomas,…
