Congenital Smooth Muscle Hamartoma Steven D. Billings, MD Key Facts Terminology Rare lesion presenting in infants, characterized by disorganized proliferation of benign smooth muscle bundles in dermis, often involving subcutis…
Superficial Malignant Peripheral Nerve Sheath Tumor David R. Lucas, MD Key Facts Terminology Superficial sarcoma arising from cutaneous nerve or benign nerve sheath tumor, or showing nerve sheath differentiation Etiology/Pathogenesis…
Primary Neuroendocrine (Merkel Cell) Carcinoma David Cassarino, MD, PhD Key Facts Terminology Cutaneous neuroendocrine carcinoma Clinical Issues Highly aggressive tumors with greater metastatic potential than melanoma Rare (approximately 470 cases/year…
Protocol for Specimens of Merkel Cell Carcinoma of the Skin David Casarino, MD, PhD Merkel Cell Carcinoma of the Skin Incisional Biopsy, Excision, Reexcision, Lymphadenectomy Procedure ____ Biopsy, incisional ____…
Peripheral Neuroepithelioma/Primitive Neuroectodermal Tumor Alexandros D. Polydorides, MD, PhD Key Facts Terminology Rare malignant small round blue cell tumor Variable evidence of neuroectodermal differentiation Etiology/Pathogenesis From neural crest cells or…
Ectopic Meningioma Cyril Fisher, MD, DSc, FRCPath Lester D. R. Thompson, MD Key Facts Terminology Benign neoplasm of meningothelial cells Clinical Issues Can present in skin of scalp Approximately 0.2%…
Nasal Glial Heterotopia Lester D. R. Thompson, MD Key Facts Etiology/Pathogenesis Congenital malformation of displaced normal and mature glial tissue Clinical Issues Separated into extranasal and intranasal types NGH usually…
Perineurioma Lester D. R. Thompson, MD Key Facts Terminology Benign peripheral nerve sheath tumor, specifically of perineurial cell derivation that surrounds endoneurial connective tissue space of nerve fibers Etiology/Pathogenesis May…
Fibrolipomatous Hamartoma of Nerve Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Increased fibrofatty tissue infiltrating and surrounding nerves Clinical Issues Median nerve most commonly affected Predominantly in children, including…
Granular Cell Tumor Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Benign tumor composed of poorly demarcated accumulation of plump granular cells Thought to arise from Schwann cells Granular cell…
