Ewing Sarcoma/PNET of Soft Tissue Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Family of small round cell translocation-associated sarcomas occurring in bone, soft tissue, or skin Additionally, PNET shows…

Melanotic Neuroectodermal Tumor of Infancy Jeremy Wallentine, MD Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Rare, fast-growing, pigmented neoplasm, likely of neural crest origin Clinical Issues Most present in…

Paraganglioma Nina Gale, MD Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Tumor arising from paraganglia Clinical Issues Variety of sites More frequent in head and neck Thorax, abdomen, larynx,…

Malignant Peripheral Nerve Sheath Tumor David R. Lucas, MD Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Sarcoma arising from a nerve or benign nerve sheath tumor or showing nerve…

Ganglioneuroma Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Benign, well-differentiated tumor of neurogenic origin Etiology/Pathogenesis Usually develop de novo Clinical Issues Most commonly located in posterior mediastinum Also in…

Ependymoma Elizabeth A. Montgomery, MD Key Facts Terminology Cellular glial or epithelial-appearing neoplasm manifesting ependymal differentiation as either perivascular rosettes or true rosettes Myxopapillary variant has pseudopapillary architecture and intercellular…

Ectopic Meningioma Lester Thompson, MD Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Benign neoplasm of meningothelial cells Clinical Issues Approximately 0.2% of sinonasal tract and nasopharynx tumors M:F= 1:1.2…

Perineurioma Thomas Mentzel, MD Key Facts Terminology Benign mesenchymal neoplasm composed of neoplastic perineural cells Clinical Issues Progressive muscle weakness &/or sensory disturbances are seen in intraneural perineurioma Extraneural perineurioma…

Nasal Glioma Steven D. Billings, MD Key Facts Terminology Rare congenital anomaly Clinical Issues Subcutaneous mass Bridge of nose most common site 1/3 are intranasal 20% associated with communication to…