HISTOLOGY

Transmission electron microscopy

Dec 13, 2017 by in HISTOLOGY Comments Off on Transmission electron microscopy

22 Transmission electron microscopy Anthony E. Woods, John W. Stirling The fundamental advantage of transmission electron microscopy (TEM) over conventional light microscopy is that the electron microscope has a resolution…

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Immunohistochemical techniques

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18 Immunohistochemical techniques Peter Jackson, David Blythe Introduction The introduction of prognostic and predictive markers in immunohistochemistry has made a tremendous beneficial impact on patient diagnosis and management. This has…

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Immunohistochemistry quality control

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20 Immunohistochemistry quality control Tracy Sanderson, Gregory Zardin Introduction Since its introduction into routine histopathology in the 1980s, immunohistochemistry has become established as an integral part of the diagnostic process….

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Light microscopy

Dec 13, 2017 by in HISTOLOGY Comments Off on Light microscopy

3 Light microscopy John D. Bancroft, Alton D. Floyd Light and its properties Visible light occupies a very narrow portion of the electromagnetic spectrum. The electromagnetic spectrum extends from radio…

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Fixation of tissues

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4 Fixation of tissues Anthony Rhodes Introduction Appropriate fixation of tissues for histological examination is extremely important. Without attention to this process, the range of tests performed in a modern…

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Pigments and minerals

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13 Pigments and minerals Guy E. Orchard Introduction In biology, pigments are defined as substances occurring in living matter that absorb visible light (electromagnetic energy within a narrow band that…

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Bone

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16 Bone Diane L. Sterchi Introduction Bone is considered the most important supporting tissue in the body. It is composed of cells, organic extracellular matrix and inorganic salts. Bone tissue…

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Molecular pathology

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21 Molecular pathology Diane L. Sterchi, Caroline Astbury Introduction Molecular pathology seeks to apply gene expression against morphology and use gene expression analysis to validate large numbers of targets. A…

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Microorganisms

Dec 13, 2017 by in HISTOLOGY Comments Off on Microorganisms

15 Microorganisms Jeanine H. Bartlett Introduction We have all heard the expression, ‘The world is getting smaller’. Nowhere is that statement truer than in the world of microorganisms. Microorganisms (also…

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Amyloid

Dec 13, 2017 by in HISTOLOGY Comments Off on Amyloid

14 Amyloid Janet A. Gilbertson, Toby Hunt Introduction History Amyloidosis is a disorder of protein folding, in which normally soluble proteins accumulate in the tissues as abnormal insoluble fibrils (or…

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