Polyvinylpyrrolidone Storage Disease Michael R. Lewin-Smith, MD Julie C. Fanburg-Smith, MD Key Facts Etiology/Pathogenesis PVP storage disease is phagocytic foreign body-type reactive condition Found in aerosol hair sprays, adhesives, lithographic…
Intimal Sarcoma Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Malignant neoplasm arising from intimal aspect of large blood vessels Clinical Issues Pulmonary trunk or pulmonary artery Descending thoracic or…
Silicone Reaction Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Tissue reaction to silicone (dimethylpolysiloxane) implant, liquid silicone, or silicone gel Etiology/Pathogenesis Leakage from prosthetic implant in breast Cosmetic injection…
Mycobacterial Pseudotumor Elizabeth A. Montgomery, MD Key Facts Terminology Exuberant spindle cell lesion, usually involving lymph nodes, induced by mycobacteria Clinical Issues Immunocompromised patients Majority have AIDS and often also…
Desmoplastic Small Round Cell Tumor Saul Suster, MD Elizabeth A. Montgomery, MD Cyril Fisher, MD, DSc, FRCPath Key Facts Clinical Issues Most common in children and young adults Median age:…
Amyloidoma Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Solitary localized tumor-like deposit of amyloid in absence of systemic amyloidosis Macroscopic Features Pale waxy cut surface Microscopic Pathology Amorphous acellular…
Clear Cell Sarcoma Elizabeth A. Montgomery, MD Key Facts Terminology Sarcoma showing melanocytic differentiation Malignant melanoma of soft parts Clinical Issues Young adults (3rd or 4th decade) Usually affects extremities…
Epithelioid Sarcoma Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Malignant mesenchymal tumor resembling carcinoma or granuloma Shows predominantly epithelial but also mesenchymal differentiation Occurs in classical and proximal aggressive…
Extrarenal Rhabdoid Tumor Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Malignant neoplasm of polygonal cells with characteristic large cytoplasmic inclusion and eccentric large nucleus Requires exclusion of specific tumor…
