Amyloidoma



Amyloidoma


Cyril Fisher, MD, DSc, FRCPath









Hematoxylin & eosin shows irregular-shaped amyloid deposits image with adjacent stroma containing inflammatory cells.






Congo red stain shows the intense red (congophilic) coloration of amyloid. Note the slight variation in staining intensity and the angulated shape and distinct demarcation of the deposits.


TERMINOLOGY


Synonyms



  • Tumoral amyloidosis


Definitions



  • Solitary localized tumor-like deposit of amyloid in absence of systemic amyloidosis


ETIOLOGY/PATHOGENESIS


Idiopathic



  • No associated disease


Immune Dyscrasias



  • Myeloma, plasmacytoid lymphoma


  • AL (light chain) amyloid



    • Green birefringence resistant to pre-treatment with potassium permanganate


Long-term Hemodialysis



  • β2 microglobulin deposition

Jul 9, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Amyloidoma
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