Silicone Reaction



Silicone Reaction


Cyril Fisher, MD, DSc, FRCPath









Hematoxylin & eosin shows fibrous reaction around a breast implant. There are clusters of univacuolated or multivacuolated cells, some containing refractile material image.






Hematoxylin & eosin shows a multinucleated giant cell and lymphocytic reaction around variable-sized cystic spaces in the fibrous tissue.


TERMINOLOGY


Synonyms



  • Silicone granuloma


Definitions



  • Tissue reaction to silicone (dimethylpolysiloxane) implant, liquid silicone, or silicone gel


ETIOLOGY/PATHOGENESIS


Iatrogenic



  • Leakage from prosthetic implant in breast



    • Spontaneous


    • Following trauma, including compression mammography


  • Cosmetic injection



    • Face



      • Nose, lips


    • Earlobes


    • Abdominal wall


    • Genitalia

Jul 9, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Silicone Reaction
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