Hard Shell Capsule Filling Machines
Figure 6.1Basic operations common to all filling machines. (Courtesy of IMA ACTIVE division, Bologna, Italy.) Separation The diameter of the upper bushing or housing is larger than the diameter of…
Modified-Release Delivery SystemsExtended-Release Capsule Platform
Figure 12.1(See color insert.) Approximate size spectrum showing dimensions of typical molecules, carrier types, and drug delivery systems based on the published literature and some of the commercialized nanotechnology products,…
Modeling Powder Filling during Encapsulation
Figure 10.1Capsules produced from two encapsulation methods: (a) manual filling (loose powder); (b) automatic machine (plug). Machines having five tamping stations (Bosch GKF and Höfliger-Karg machines) compress the powder once…
Plug Formation
Figure 9.1(a) Schematic drawing of a force–time profile that would be obtained on an eccentric tablet press, based on time calculations for a running speed of 43.6 rpm66 and general…
