Chapter 18 Nonsteroidal Anti-Inflammatory Drugs and other Nonopioid Analgesic-Antipyretic Drugs I. General Considerations A. Nonsteroidal anti-inflammatory drugs (NSAIDs) • Inhibit the synthesis of eicosanoids from arachidonic acid (Fig. 18-1; Table…
Chapter 30 Toxicology and Drugs of Abuse I. General Principles of Toxicology A. Definitions 1. Toxicology is the study of the hazardous effects of chemicals, including drugs, on biologic systems….
Chapter 19 Opioid Analgesics and Antagonists I. Opioid Agonists (Box 19-1) • Classified into three categories; strong, moderate, and weak A. General features 1. Mechanism of action a. The effects…
Chapter 29 Chemotherapeutic Drugs I. General Considerations • Cancer is a disease in which the cellular control mechanisms that govern proliferation and differentiation are changed. A. Pathology of cancers (See…
Chapter 25 Drugs Used in the Treatment of Bone and Calcium Disorders I. General Considerations • Parathyroid hormone (PTH) and vitamin D play a role in the regulation of calcium…
Chapter 11 Drugs Used in the Treatment of Parkinson’s Disease I. General Considerations A. Parkinsonism is associated with lesions in the basal ganglia, especially the substantia nigra and the globus…
Chapter 9 Anticonvulsant Drugs I. Anticonvulsant Therapy • Seizures are episodes of abnormal electrical activity in the brain that may lead to involuntary movements and sensations, which are accompanied by…
Chapter 17 Hematopoietic Drugs I. General Considerations A. Causes of anemia 1. Failure to produce sufficient red blood cells (RBCs) 2. Inadequate synthesis of hemoglobin 3. Destruction of RBCs 4….
Chapter 13 Antihypertensive Drugs I. General Considerations A. Classification of blood pressure for adults aged 18 years or older (Table 13-1). B. Treatment rationale 1. Sustained hypertension leads to cardiovascular…
Chapter 8 Anesthetics I. General Anesthetics A. Goals of balanced anesthesia 1. Analgesia • Elimination of perception and reaction to pain 2. Amnesia • Loss of memory, which is not…
