First-Generation Nonsteroidal Antiinflammatory Drugs (NSAIDs) Aspirin Ibuprofen Second-Generation NSAID (Selective Cyclooxygenase-2 Inhibitor) Celecoxib Drug That Lacks Antiinflammatory Actions Acetaminophen Aspirin Aspirin is a highly valuable and effective medication. The drug…
Selective Serotonin Reuptake Inhibitor Fluoxetine Serotonin-Norepinephrine Reuptake Inhibitor Venlafaxine Tricyclic Antidepressant Imipramine Monoamine Oxidase Inhibitor Phenelzine Atypical Antidepressant Bupropion Drugs Used for Depression Drugs are the primary therapy for major…
] embodies the properties that typify all muscarinic agonists and will serve as our prototype for the group. Mechanism of Action Bethanechol is a direct-acting muscarinic agonist. The drug binds…
Lithium Carbamazepine Valproic acid Treatment of Bipolar Disorder Drug Therapy Types of Drugs Employed The American Psychiatric Association (APA) and the Veterans Administration both published treatment guidelines for bipolar disorder…
Figure 45.1 Stages of red blood cell development. Development of RBCs requires the cooperative interaction of several factors: bone marrow must be healthy; erythropoietin (a stimulant of RBC maturation) must be…
Figure 64.1 The emetic response: stimuli, pathways, and receptors. CTZ, chemoreceptor trigger zone. Several types of receptors are involved in the emetic response. Important among these are receptors for serotonin, glucocorticoids, substance…
Figure 37.1 Coupling of cardiac calcium channels with beta1-adrenergic receptors. In the heart, beta1 receptors are coupled to calcium channels. As a result, when cardiac beta1 receptors are activated, calcium influx is…
Black Box Warning: Nonsteroidal Antiinflammatory Drugs NSAIDs may increase the risk for myocardial infarction, stroke, and other thromboembolic events. NSAIDs increase the risk for dangerous gastrointestinal adverse effects such as…
Figure 17.1 A model of neurotransmission in the healthy striatum and parkinsonian striatum. A, In the healthy striatum, dopamine (DA) released from neurons originating in the substantia nigra inhibits the firing of…
Isoniazid Rifampin Pyrazinamide Ethambutol TABLE 75.5 Antituberculosis Drugs: Routes and Major Adverse Effects Drug Route Major Adverse Effects FIRST-LINE DRUGS Isoniazid PO, IM Hepatotoxicity, peripheral neuritis Rifampin PO, IV Hepatotoxicity…
