Basicmedical Key

DDCCMTLow-power examination shows a dermal-based clear cell tumor with a nonencapsulated lateral border . (Courtesy A. Lazar, MD, PhD.) DDCCMT at Higher MagnificationHigher magnification examination shows a dermal-based clear cell…

Lymphoepithelioma-Like Carcinoma of the SkinHigh magnification of lymphoepithelioma-like carcinoma of the skin (LELCS) shows a prominent lymphohistiocytic infiltrate obscuring a background of large, undifferentiated epithelioid-appearing cells . Low Magnification of…

Desmoplastic FibroblastomaLow-magnification examination of a desmoplastic fibroblastoma is shown. The lesion is a well-circumscribed ovoid or fusiform mass. The characteristic hypocellularity is apparent at low power. Desmoplastic Fibroblastoma With Deep…

 Architecturally more complex  Multiloculated  Squamous eddies  Mitotic activity • Malignant proliferating pilar cyst/tumor  Infiltrative growth  Cytologic atypia and mitotic activity • Epidermoid cyst  Well-developed granular layer  Epidermal keratinization • Hybrid cyst  Has distinct…

 Mechanical dermabrasion, retinoids, needle evacuation, simple excision, or laser therapy Microscopic • Dermal cyst lined by bland stratified squamous epithelium with granular layer • Intraluminal laminated keratin debris and numerous vellus hair…

 Gorlin-Goltz syndrome: Multiple cutaneous basal cell carcinomas, odontogenic keratocysts of jaw, palmar and plantar pits, rare medulloblastomas, and skeletal abnormalities • Rare cases not associated with NBCCS also reported Clinical Issues…