Distinctive Dermal Clear Cell Mesenchymal Tumor


DDCCMT
Low-power examination shows a dermal-based clear cell tumor with a nonencapsulated lateral border image. (Courtesy A. Lazar, MD, PhD.)



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DDCCMT at Higher Magnification
Higher magnification examination shows a dermal-based clear cell tumor with a thin grenz zone image separating it from the overlying epidermis. (Courtesy A. Lazar, MD, PhD.)

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DDCCMT at High Magnification
High magnification shows the relatively bland cytologic features of the large clear cells with vesicular nuclei, focally enlarged nucleoli image, and abundant clear cytoplasm. (Courtesy A. Lazar, MD, PhD.)

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DDCCMT: Cytologic Features
Higher magnification shows relatively bland cytologic features of large clear cells, which show enlarged nuclei with vesicular chromatin and focally prominent nucleoli image. Cytoplasm is predominantly clear to focally granular-appearing. (Courtesy A. Lazar, MD, PhD.)


TERMINOLOGY


Abbreviations




• Distinctive dermal clear cell mesenchymal tumor (DDCCMT)


Synonyms




• Distinctive dermal clear cell mesenchymal neoplasm


Definitions




• Rare, dermal-based clear cell tumor of unclear derivation


ETIOLOGY/PATHOGENESIS


Unknown




• Very rare tumors of unknown etiology


CLINICAL ISSUES


Epidemiology




• Incidence
image Extremely rare

• Age
image Reported in adults over age 35


Site




• Most cases have occurred on lower extremities


Presentation




• Cutaneous nodule

Apr 24, 2017 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Distinctive Dermal Clear Cell Mesenchymal Tumor
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