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4 Overview of Epithelial Barriers Floriane Laurent, Anya M. Hillery, and Randall Mrsny CONTENTS 4.1  Introduction 4.2  Epithelia 4.2.1  General Organization 4.2.2  Polarity Properties 4.2.3  Regulation of Barrier Properties 4.3  Transport across Epithelia 4.3.1  Paracellular Pathway 4.3.2  Transcellular…

5 Nanotechnologies for Drug Delivery and Targeting Opportunities and Obstacles Alexander T. Florence and Daan J.A. Crommelin CONTENTS 5.1  Introduction 5.1.1  Rationale for the Development of Parenteral Drug Delivery and Targeting Systems…