Clinical and Radiologic Features
Signs and symptoms Percent patients Pulmonary Dyspnea [1, 7, 23, 24, 31, 47] 35–82 Pleural effusion [6, 7, 31, 85] 54–87 Chest pain [1, 7, 23, 24, 31, 47, 85]…
Immunohistochemistry
More likely to be positive in malignant mesothelioma P53 EMA GLUT-1 IMP3 Claimed to be positive in benign mesothelial proliferation Desmin Diffuse Malignant Mesothelioma Versus Other Malignancies Involving the Pleura…
Epidemiology
Fig. 2.1 Age-adjusted rates of malignant mesothelioma in the USA according to gender. (Adapted from SEER data) Fig. 2.2 Age-adjusted SEER incidence rates of mesothelioma from 1975–2009 according to gender…
Molecular Characteristics
Study Method Subtype Normal 3p 9p Chr. 22 Other Gibas 1986 Cytogenetics Epithelioid 1/8 (13 %) 4/8 (50 %) 3/8 (38 %)a Loss chr. 22 2/8 (25 %) Translocation 22q 1/8 (13 %) Biphasic 0/4…
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