Squamous/Adenosquamous Carcinoma, Gallbladder Joseph Misdraji, MD Key Facts Terminology Squamous cell carcinoma shows only squamous differentiation whereas adenosquamous carcinoma shows both glandular and squamous differentiation Clinical Issues 1.4-9.6% of gallbladder…
Biliary Papillomatosis Laura Webb Lamps, MD Key Facts Terminology Multiple adenomas of bile ducts Clinical Issues Very rare; some cases associated with familial adenomatous polyposis Resection often not possible given…
Intestinal-type Adenoma Vikram Deshpande, MD Key Facts Terminology Gallbladder polyp composed of intestinal-type epithelium Clinical Issues Progression to carcinoma uncommon Microscopic Pathology Resemble colonic adenomas Tubular, papillary to mixed tubulopapillary…
Pyloric Gland Adenoma Vikram Deshpande, MD Key Facts Terminology Benign neoplasm of glandular epithelium showing pyloric differentiation Clinical Issues Usually discovered incidentally Macroscopic Features Usually solitary sessile lesions Microscopic Pathology…
Lymphoepithelial Cysts Grace E. Kim, MD Key Facts Clinical Issues Rare nonneoplastic pancreatic cystic lesions composed of squamous epithelial and lymphoid elements Macroscopic Features Multilocular or unilocular cystic lesions Microscopic…
Diabetes Mellitus Laura Webb Lamps, MD Key Facts Terminology Heterogeneous group of metabolic diseases characterized by hyperglycemia, generally classified as types 1 and 2 Macroscopic Features Decreased size and weight…
Pseudocysts Vikram Deshpande, MD Key Facts Terminology Pancreatic or peripancreatic collection of fluid rich in pancreatic enzymes Etiology/Pathogenesis Occurrence parallels that of pancreatitis Alcoholic abuse is leading cause Macroscopic Features…
Autoimmune Pancreatitis Mari Mino-Kenudson, MD Key Facts Terminology Fibroinflammatory disease of presumed autoimmune etiology that affects pancreas Often elevated serum IgG4 Similar fibroinflammatory process often affects other organs such as…
Polyarteritis Nodosa and Other Vasculitides Laura Webb Lamps, MD Key Facts Etiology/Pathogenesis Liver and gallbladder involved in > 40% of cases of polyarteritis nodosa (PAN) Gallbladder involvement occasionally isolated rather…
Eosinophilic Cholecystitis Vikram Deshpande, MD Key Facts Terminology Inflammatory disease of gallbladder in which inflammatory infiltrate is composed predominantly of eosinophils Microscopic Pathology Dense eosinophilic infiltrate of gallbladder with or…
