Primary Cutaneous Anaplastic Large Cell Lymphoma
Primary Cutaneous Anaplastic Large Cell Lymphoma C. Cameron Yin, MD, PhD Key Facts Terminology Cutaneous lymphoma composed of large T cells that express CD30 (> 75%) Clinical Issues Common sites:…
Lymphocyte-rich Classical Hodgkin Lymphoma
Lymphocyte-rich Classical Hodgkin Lymphoma Sa A. Wang, MD Key Facts Terminology Type of CHL in which small reactive lymphocytes predominate and are associated with HRS cells Clinical Issues 4-5% of…
Intravascular Large B-cell Lymphoma
Intravascular Large B-cell Lymphoma Francisco Vega, MD, PhD Key Facts Terminology Rare large B-cell lymphoma characterized by selective intravascular growth Clinical Issues Absence of marked lymphadenopathy Middle-aged or elderly patients…
Lymphomatoid Papulosis
Lymphomatoid Papulosis C. Cameron Yin, MD, PhD Key Facts Terminology Chronic, self-healing and recurrent erythematous papules/nodules on skin of trunk and extremities Clinical Issues Usually remains confined to skin Excellent…
Post-transplant Lymphoproliferative Disorder, Early Lesions and Polymorphic
Post-transplant Lymphoproliferative Disorder, Early Lesions and Polymorphic C. Cameron Yin, MD, PhD Pei Lin, MD Key Facts Etiology/Pathogenesis Epstein-Barr virus infection and impaired host immunosurveillance important 80% of all PTLDs…
Nodal Marginal Zone B-cell Lymphoma
Nodal Marginal Zone B-cell Lymphoma Pei Lin, MD Key Facts Clinical Issues Age: 5th-6th decades No evidence of extranodal or splenic lymphoma Can transform to diffuse large B-cell lymphoma Microscopic…
Subcutaneous Panniculitis-like T-cell Lymphoma
Subcutaneous Panniculitis-like T-cell Lymphoma Tariq Muzzafar, MBBS Key Facts Terminology Cytotoxic T-cell lymphoma that preferentially involves subcutaneous tissue and expresses TCR-αβ Definition of SPTCL substantially revised in WHO 2008 classification…
Antibody Index
Antibody Index Antibodies Discussed Antibody Symbol/Name Antibody Description Clones/Alternative Names β-2-microglobulin component of MHC class I molecules B2-MICROGLB κ light chain kappa light chain KAPPA λ light chain lambda light…
Enteropathy-associated T-cell Lymphoma
Enteropathy-associated T-cell Lymphoma Sa A. Wang, MD Key Facts Terminology T-cell lymphoma of intestine Arises from intraepithelial T cells Etiology/Pathogenesis Classical cases of EATL arise in patients with evidence of…
Palisaded Myofibroblastoma
Palisaded Myofibroblastoma L. Jeffrey Medeiros, MD Key Facts Terminology Intranodal palisaded myofibroblastoma Synonyms Intranodal hemorrhagic spindle-cell tumor with amianthoid fibers Myofibroblastoma Clinical Issues Rare benign tumor of probable myofibroblastic origin…
