Antibodies Discussed

Antibody Symbol/Name

Antibody Description

Clones/Alternative Names

β-2-microglobulin

component of MHC class I molecules

B2-MICROGLB

κ light chain

kappa light chain

KAPPA

λ light chain

lambda light chain

LAMBDA

Actin-HHF-35

actin, muscle (HHF35)

MSA, HHF-35

Actin-sm

actin, smooth muscle

SMA, ASM-1, CGA7, IA4, HUC-1

AE1/AE3

AE1/AE3; mixture of 2 anticytokeratin clones that detect a variety of both high and low molecular weight cytokeratins

ALK1

anaplastic lymphoma kinase-1

SA4, ALK, ALKC

Androgen receptor

dihydrotestosterone receptor, nuclear subfamily 3, group C, member 4

AR441, F39.4.1, AR-N20, AR27

Annexin-A1

mediator of anti-inflammatory response and upregulated in hairy cell leukemia

ANXA1, LPC1, lipocortin

BAD

bcl-2-associated agonist of cell death

Bartonella henselae

B. henselae

B-henselae, cat scratch fever agent

BAX

bcl-2-associated X protein

PU-347-P, B-9, BAX-P, P19, BAX-M

Bcl-2

B-cell CLL lymphoma 2; suppresses apoptosis in a variety of cell systems

ONCL2, BCL2/100/D5, 124, 124.3

Bcl-6

B-Cell CLL lymphoma 6

LN22, GI191E/A8, N-3, PG-B6P, P1F6, 3FR-1

BDCA-2

Monoclonal antibody directed toward immature plasmacytoid dendritic cells

CD303

BF1

T-cell antigen receptor

TCR

BOB1

B-cell OCT-binding protein 1

SC955, BOB.1

Caldesmon

actin interacting and calmodulin binding protein found in smooth muscle and other cell types

CAD, CALD1, caldesmon 1 isoform [1-5], CDM, HCAD, LCAD, MGC21352, NAG22

CD1a

T-cell surface glycoprotein

JPM30, CD1A, O10, NA1/34

CD2

T-cell surface antigen, LFA2

271, MT910, AB75, LFA-2

CD2AP

CD2 associated protein

CD3

T-cell receptor

F7238, A0452, CD3-P, CD3-M, SP7, PS1

CD3-ε

T cell surface antigen T3/Leu-4 epsilon chain

CD3E, CD03e

CD4

T-cell surface glycoprotein L3T4

IF6, 1290, 4B12

CD5

T-cell surface glycoprotein Leu 1, T1

NCL-CD5, 4C7, 54/B4, 54/F6

CD7

T-cell antigen precursor Leu 9

272, CD7-272

CD8

T-cell coreceptor antigen, Leu 2, T-cytotoxic cells

M7103, C8/144, C8/144B

CD10

neutral endopeptidase

CALLA, neprilysin, NEP

CD11c

integrin alpha X chain protein

LEU-M5

CD12

CDw12

CD13

plays role in growth of DC/macrophage progenitors and precursors

CD15

reacts with Reed-Sternberg cells of Hodgkin disease and with granulocytes

VIM-2,3C4, LEU-M1, TU9, VIM-D5, MY1, CBD1, MMA, 3CD1, C3D1, Lewis x, SSEA-1

CD16

Fc receptor of IgG

CD19

B-cell antigen

CD20

membrane spanning 4 domains of B-lymphocytes

FB1, B1, L26, MS4A1

CD21

CR2, complement component receptor 2, Epstein-Barr virus receptor

IF8

CD22

B-cell receptor

FPC1, LEU 14

CD23

Fc ∈ RII, low-affinity IgE receptor,

IGEBF 1B12, MHM6BU38

CD25

If-2 receptor alpha

2A3, 4C9

CD26

ADA adenosine deaminase complexing protein 2, DPP4

44-4

CD27

TNF receptor

CD29

fibronectin receptor, integrin beta 1 ITGB1

29C03, 7F10, HT29_12938

CD30

tumor necrosis factor SF8

BER-H2, KI-1, TNFRSF8

CD31

platelet endothelial cell adhesion molecule

JC/70, JC/70A, PECAM-1

CD33

SIGLEC lectin 3

PWS44

CD34

hematopoietic progenitor cell antigen

MY10, IOM34, QBEND10, 8G12, 1309, HPCA-1, NU-4A1, TUK4, clone 581, BI-3c5

CD35

erythrocyte complement receptor 1, immune adherence receptor, C3b/C4b receptor

CR1, BER-MAC-DRC, TO5C, E11

CD38

acute lymphoblastic T-cell antigen, T10

SPC32, VS38, T10

CD43

Major sialoglycoprotein on surface of human T lymphocytes, monocytes, granulocytes, and some B lymphocytes

LEU-22, DF-T1, L60, MT1, sialophorin, leukosialin, SPN

CD44

cell adhesion receptor for hyaluronic acid HCAM

9B5, HCAM, CD44H, B-F24, A3D8, 2C5, CD44S, F10-44.2, 156-3C11, DF1485, BBA10, VFF-14, CD44V10, CD44V3, 3G5, CD44V3-10-P, CD44V3-10, 3D2, CD44V4_5, CD44V5, VFF-8, VFF-7, 2F10, VFF-18, CD44V6, CD44V7, VFF-9, CD44V7_8, VFF-17

CD45

leukocyte common antigen

LCA, PD7/26, 1.22/4.14, T29/33, RP2/18, PD7, 2D1, 2B11+PD7/26

CD45RA

isoform of CD45 expressed by naive T cells

4Kb5, MT2, MB1

CD45RO

isoform of CD45 located on memory T cells

ICH1-L, low molecular weight isoform LCA

CD54

ICAM-1 (intracellular adhesion molecule 1)

23G12, CD54-P, ICAM

CD56

NCAM (neutral cellular adhesion molecule)

MAB735, ERIC-1, 25-KD11, 123C3, 24-MB2, BC56C04, 1B6, 14- MAB735, NCC-LU-243, MOC-1, NCAM

CD57

β-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)

LEU-7, NK1, HNK-1, TB01, B3GAT1

CD68

cytoplasmic granule protein of monocytes, macrophages

PG-M1, KP-1, LN5

CD72

B-cell differentiation antigen

DBA.44

CD79-α

immunoglobulin-associated alpha, MB1

MB-1, 11D10, 11E3, CD79A, HM47/A9, HM57, JCB117

CD103

CD117

C-kit; tyrosine protein kinase activity

C-19 (C-KIT), 104D2, 2E4, C-KIT, A4502, H300, CMA-767

CD123

receptor for IL-3 (IL-3R)

CD138

syndecan; a useful marker for plasma cells

B-B4, AM411-10M, MI15

CD163

macrophage hemoglobin scavenging system

10D6

CD303

monoclonal antibody directed toward immature plasmacytoid dendritic cells

BDCA-2

CEA-M

carcinoembryonic antigen, monoclonal

CEA-B18, CEA-D14, CEA-GOLD 1, T84.6, CEA-GOLD 2, CEA 11, CEA-GOLD 3, CEA 27, CEA-GOLD 4, CEA 41, CEA-GOLD 5, T84.1, CEA-M, A5B7, CEJ065, IL-7, T84.66, TF3H8-1, 0062, D14, alpha-7, PARLAM 1, ZC23, CEM010, A115, COL-1, AF4, 12.140.10, 11-7, M773, CEA-M431_31, CEJO65, mCEA

Centerin

Serine proteinase inhibitor A11 antibody. May play an important role in GC-B cell physiology; expression in lymphomas can be important in differential diagnosis

GCET1, seprin A9, Serpina 11b, Serpina9

CK-PAN

cytokeratin-pan (AE1/AE3/LP34); cocktail of high and low molecular weight cytokeratins

keratin pan, MAK-6, K576, LU-5, KL-1, KC-8, MNF 116, pankeratin, pancytokeratin

CK20

Cytokeratin 20, low molecular weight cytokeratin with expression most commonly restricted to GI tract

KS20.8

CLA

cutaneous lymphocyte antigen

CLA-HECA452

Clusterin

clusterin, alpha chain specific

41D, E5

CMV

cytomegalovirus

CRP

c-reactive protein

CTLA-4

cytotoxic T-lymphocyte antigen 4

BN13

CXCL13

chemokine CXC ligand 13

53610, B lymphocyte chemoattractant (BLC)

CXCR3

chemokine CXC receptor R3

1C6

Cyclin-D1

Protein with important cell cycle regulatory functions; proto-oncogene; regulator of cell cycle progression (G1 to S-phase)

A-12, PRAD1, AM29, DCS-6, SP4, 5D4, D1GM, P2D11F11

Cyclin E

key regulator of G/S transition in cell cycle; overexpression observed in several malignancies associated with high proliferation

13A3, HE12

D11

homeobox D11

HOXD11

DBA.44

CD72, B-cell differentiation antigen

CD72

Desmin

class III intermediate filaments found in muscle cells

M760, DE-R-11, D33, DE5, DE-U-10, ZC18

E2A

immunoglobulin enhancer-binder factor E12/E47

EBER

Epstein-Barr virus encoded RNA

EBNA2

Epstein-Barr virus-associated nuclear antigen 2

EBV-LMP

Epstein-Barr virus latent membrane protein

LMP1, CS 1-4

EBV-LMP1

viral protein produced during latent cycle of EBV infection

EGFR

v-erb b1 erythroblastic leukemia viral gene, epidermal growth factor receptor

2-18C9, EGFR1, EGFR PHRMDX, NCL-R1, H11, C-ERBB-1, E30, EGFR.113, 31G73C6, 2-18C9

EMA

epithelial membrane antigen

GP1.4, 214D4, MC5, E29, MUC1, EMA/MUC1

Factor XIIIa

factor-XIIIA (fibrin stabilizing factor)

FXIIIA

FAS

CD 95 (Fas receptor (FasR)

CD95, fatty acid synthase, APO-1, UB2, B10

Fascin

singed-like protein

55K2, FAN1, Fascin 1, FSCN1, p55, SNL, singed like protein antibody

FOXP1

forkhead box transcription factor P3

JC12

GZM-B

Granzyme B; neutral serine protease

11F1, GR-B7, Granzyme B

H-caldesmon

high molecular weight caldesmon

HCAD, H-CD

Helicobacter pylori

H. pylori

H-pylori

HGAL

human germinal center-associated lymphoma

HHV8

human herpesvirus-8 latent nuclear antigen-1

13B10, LNA-1, Kaposi sarcoma associated herpes virus, KSHV

HLA-DR

human leukocyte antigen DR

DK22, LN3, TAL.1B5, LK8D3

HMB-45

antigen present in melanocytic tumors such as melanomas

LB39 AA, CMM1, CMM, DNS, FAMMM, Mart1, Melan-A, MLM, tyrosinase

HPV

human papillomavirus

HSV1/2

herpes simplex virus 1/2

HSV1/HSV2

ID2

DNA binding protein inhibitor

IgA

immunoglobulin A

IGA

IgD

immunoglobulin D

IGD

IgM

immunoglobulin M

IGM

IL-13

interleukin 13

IRF-4

interferon regulatory factor 4

MUM1P, clone MUM1, MUM1-IRF.4, MUM1, M17

J chain

immunoglobulin joining segment

NFGD11

Ki-67

Ki-67 (MIB-1); marker of cell proliferation

MMI, KI88, IVAK-2, MIB1

L1

neural adhesion molecule

UJ127, CD171

LANA1

latency associated nuclear antigen of HHV8

Human herpes 8 latent nuclear antigen, LN53

Langerin

CD207 molecule

CD207

LCA

leukocyte common antigen

PD7/26, 1.22/4.14, T29/33, CD45RB, RP2/18, CD45, PD7, 2D1, 2B11+PD7/26

LMP1

Epstein Barr virus- latent membrane protein

EBV-LMP, CS 1-4

Lysozyme

1,4-beta N-acetylmuramidase C

Lyz, Lzm, Ec3.2.1.17

M1

gastric superficial/foveolar cells

M2

Cyclin dependent kinase 2

CDK2

Melan-A

melanoma antigen recognized by T cells 1 (MART-1); protein found on melanocytes; melanocyte differentiation antigen

M2-7C10, CK-MM

Melan-A103

clone of Melan-A

A103

met

met protooncogene

8F11, C-28, C-MET

MK

neurite growth promoting factor 2

Midkine, G2a,

MPO

myeloperoxidase

MT

metallothionein

Clone E9

Mucosal homing receptor

role in lymphocyte homing to mucosal lymphoid tissues

Integrin-α4β7

MUM1

Interferon regulatory factor 4

IRF-4, MUM1P, clone MUM1, MUM1-IRF.4, M17

MxA

Protein induced by alpha interferon protein

Myosin

motor protein responsible for actin-based motility

N3

calponin

calponin, calp

NOTCH1

translocation-associated notch protein

p16

cyclin-dependent kinase 4 inhibitor 2A

P16_INK4A, E6H4, sc1661, JC8, JZ11, P16, G175-405, F-12, DCS-50, 6H12, 16P07, 16P04

p21

cyclin-dependent kinase inhibitor 1A

WAF1, DCS-60.2, EA10, 6B6, 4D10, SX118, P21, P21_WAF1, WAFT

p53

p53 tumor suppressor gene protein

DO7, 21N, BP53-12-1, AB6, CM1, PAB1801, DO1, BP53-11, PAB240, RSP53, MU195, P53

p63

tumor protein p63

H-137, 7JUL

pax-5

paired box gene 2

Z-RX2, PAX-2

PD-1

programmed cell death protein 1

EH12, NAT105, Programmed death 1

Perforin

P1-8, PE-41-PU, 5B10

PR

progesterone receptor

10A9, PGR-1A6, KD68, PGR-ICA, PRP-P, PRP, PRI, 1A6, 1AR, HPRA3, PGR-636, 636, PR88, NCL-PGR

PU.1

transcription factor PU.1

G148-74

S100

Low molecular weight protein normally present in cells derived from neural crest (Schwann cells, melanocytes, and glial cells), chondrocytes, adipocytes, myoepithelial cells, macrophages, Langerhans cells, dendritic cells, and keratinocytes

S-100, A6, 15E2E2, Z311, 4C4.9, S100 protein

TCL1

trophoblast membrane protein 1

NDOG1

TCR

T-cell receptor antigen

T_Cell_AG_R, Beta-F1, 8A3, BF1

TCR-αβ

T-cell receptor heterodimer composed of an alpha and a beta chain

TCR-β

Antibody directed toward the beta chain of the TCR-αβ heterodimer

TCR-γ

T-cell receptor gamma chain

TCR-gamma

TCR-γδ

T cell receptor heterodimer composed of a gamma and a delta chain

TdT

terminal deoxynucleotidyl transferase

SEN28

TF

Thomasen-Friedenreich blood group antigen

HB-T1

Thyroglobulin

dimetric protein specific to thyroid gland

DAK-TG6

TIA

T-cell intracellular antigen 1

NS/1-AG4, 2G9, TIA-1

TNF-α

Antibody directed toward the alpha chain of the TCR-αβ heterodimer

TRAF1

tumor necrosis factor receptor 1

TRAP

tartrate-resistant acid phosphatase

26E5, 9C5

Tryptase

serine proteinase contained in mast cells

AA1

Tyrosinase

catalyzes production of melanin

NCL-TYROS, T311

VEGF

vascular endothelial growth factor

JH121, 26503.11, VPF, VPF/VEGF, VEGF-A, VEGF-C, RP 077, VEGFR-1, RP 076, VEGFR-2, 9D9, VEGFR-3, FLT-4

Vimentin

major subunit protein of intermediate filaments of mesenchymal cells

43BE8, 3B4, V10, V9, VIM-B34, VIM

VS38

type II transmembrane glycoprotein expressed on many types of immune cells (i.e., activated T-cells, precursor and activated B-cells, plasma cells, monocytes, peripheral NK -cells, and early bone marrow precursor cells)

CD38, SPC32, VS38, T10

WT1

Wilms tumor gene 1

6F-H2, C-19

ZAP70

SYK-ZAP-70 protein

2F3.2, ZAP-70, ZAP-70-LR