Plexiform Fibrohistiocytic Tumor Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Fibrohistiocytic tumor of intermediate malignant potential Microscopic Pathology Tumor based at dermal-subcutaneous junction Infiltrative, plexiform, or multinodular growth pattern…
Distinctive Dermal Clear Cell Mesenchymal Tumor David Cassarino, MD, PhD Key Facts Terminology Rare, dermal-based clear cell tumor of unknown derivation Clinical Issues Cutaneous nodule Most cases have been reported…
Superficial Acral Fibromyxoma Thomas Mentzel, MD Key Facts Terminology Benign fibroblastic neoplasm with predilection for hands and feet Clinical Issues Rare tumor Dermal &/or subcutaneous neoplasm Mainly adults Biologically benign…
Cutaneous Myxoma and Angiomyxoma Steven D. Billings, MD Key Facts Etiology/Pathogenesis May be associated with Carney complex (also known as NAME and LAMB syndromes) If patient has multiple cutaneous myxomas,…
Giant Cell Tumor of Tendon Sheath David R. Lucas, MD Key Facts Terminology Localized tenosynovial giant cell tumor, localized PVNS, nodular tenosynovitis Etiology/Pathogenesis Balanced translocation involving 1p13 (CSF1 gene) in…
Multinucleate Cell Angiohistiocytoma David Cassarino, MD, PhD Key Facts Terminology Proliferation of vessels and multinucleated stromal cells Etiology/Pathogenesis May be nonneoplastic reactive process Clinical Issues Usually occurs in patients >…
Angiomyofibroblastoma Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Benign stromal tumor composed of numerous capillaries and myofibroblasts Clinical Issues Women of reproductive age Arises in vulva or vagina Often…
Digital Fibromatosis (Infantile Digital Fibromatosis) Elizabeth A. Montgomery, MD Key Facts Terminology Benign proliferation of fibroblasts and myofibroblasts containing scattered eosinophilic inclusion bodies that occur on digits of young children…
Fibrous Hamartoma of Infancy Elizabeth A. Montgomery, MD Key Facts Terminology Benign superficial fibrous lesion occurring during 1st 2 years of life Clinical Issues Congenital in up to 25% of…
Dermatomyofibroma David Cassarino, MD, PhD Key Facts Terminology Myofibroblastic tumor with features overlapping with dermatofibroma Clinical Issues Slow-growing plaque or nodule Most cases present in shoulder and axillary regions Microscopic…
