Pseudosarcomatous Fibroblastic Proliferations Elizabeth A. Montgomery, MD Key Facts Terminology Nodular fasciitis: Rapidly growing myofibroblastic proliferation that is often cellular and mitotically active, but behaves in a benign fashion Intravascular…
Arteriovenous Hemangioma (Malformation) Steven D. Billings, MD Key Facts Terminology Acral arteriovenous tumor Cirsoid aneurysm Benign vascular tumor composed of thick- and thin-walled blood vessels Microscopic Pathology Circumscribed tumor in…
Infantile (Juvenile) Hemangioma Jeremy C. Wallentine, MD Key Facts Clinical Issues Most common tumor of infancy Appear within 1st few weeks of life Rapidly enlarge over several months All eventually…
Myxofibrosarcoma David Cassarino, MD, PhD Key Facts Terminology Myxofibrosarcoma represents a spectrum of malignant fibroblastic neoplasms with variably myxoid stroma and characteristic elongated curvilinear vessels Clinical Issues One of most…
Vascular Hamartomas Steven D. Billings, MD Key Facts Clinical Issues Port-wine stain Usually involves head and neck Sturge-Weber syndrome Port-wine stain involving ophthalmic branch of trigeminal nerve Klippel-Trenaunay-Weber syndrome Port-wine…
Cutaneous Malignant Fibrous Histiocytoma/Pleomorphic Sarcoma Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Anaplastic sarcoma composed of pleomorphic spindle and polygonal cells No other definable differentiation, other than fibroblastic or…
Low-Grade Fibromyxoid Sarcoma (Evans Tumor) Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Malignant fibroblastic neoplasm composed of bland spindle cells in collagenous matrix, often with prominent collagenous nodules Characterized…
Dermatofibrosarcoma Protuberans David Cassarino, MD, PhD Key Facts Terminology Low-grade malignant spindle cell tumor of skin characteristically showing prominent storiforming Variant: Bednar tumor (pigmented DFSP) Clinical Issues Typically occurs in…
Fibrosarcoma Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Soft tissue sarcoma composed of fibroblasts Lacks features of specific types of fibrosarcoma Etiology/Pathogenesis Exceptionally rare if strictly defined Microscopic Pathology…
Angiomatoid Fibrous Histiocytoma Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Rare neoplasm of intermediate biologic potential Most often arises in extremities of children and young adults Histologically often confused…
