The Essentials of Light Microscopy
Fig. 5.1 Conjugate planes in the optical microscope (cutaway). In this cutaway of a modern microscope, “image” planes are marked in black while “aperture” planes are marked in red, denoting…
Basic Cytogenetics Laboratory Procedures
Overview of cell culture and harvest Culture initiation → Culture maintenance → Cell harvest Living cells→ Sterility→ Arrest division Sterility→ Optimal temperature→ Swell cells Proper growth medium→ Optimal pH→ Fix…
Fragile X—A Family of Disorders: Changing Phenotype and Molecular Genetics
Name Location Type FRAXA Xq27.3 Rare FRAXB Xp22.31 Common FRAXC Xq22.1 Common FRAXD Xq27.3 Common FRAXE Xq28 Rare FRAXF Xq28 Rare Fig. 19.1 Appearance of FRAXA. (a) Conventional stain (Giemsa)…
Genomic Imprinting and Uniparental Disomy
Fig. 20.1 Diagrammatic representation of the imprinting process. Light-colored circles represent undermethylated genes, dark-colored circles represent hypermethylated genes. m maternally derived chromosome, pink. p paternally derived chromosome, blue. See text…
The Cytogenetics of Infertility
Fig. 11.1 Flow diagram for the workup of a woman with delayed puberty (Courtesy of Dr. Lawrence Layman.) PCOS polycystic ovary syndrome, CAIS complete androgen insensitivity syndrome, FSH follicle-stimulating hormone,…
Genetic Counseling
Fig. 21.1 Pedigree of a family carrying a balanced translocation involving the long arm of chromosome 7 and the short arm of chromosome 10. See key for interpretation of symbols…
Quality Control and Quality Assurance
Steven L. Gersen and Martha B. Keagle (eds.)The Principles of Clinical Cytogenetics3rd ed. 201310.1007/978-1-4419-1688-4_6© Springer Science+Business Media New York 2013 6. Quality Control and Quality Assurance Martha B. Keagle1 (1) Department of Allied Health Sciences, College of…
