Principles of Antimicrobial Chemotherapy

Jan 1, 2017 by in PHARMACY Comments Off on Principles of Antimicrobial Chemotherapy

Figure 37–1 Sites of action of antimicrobial drugs. Antimicrobial drugs include cell wall synthesis inhibitors, protein synthesis inhibitors, metabolic and nucleic acid inhibitors (e.g., inhibitors of folate synthesis, DNA gyrase,…

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Introduction to Autonomic and Neuromuscular Pharmacology

Jan 1, 2017 by in PHARMACY Comments Off on Introduction to Autonomic and Neuromuscular Pharmacology

Figure 5–1 Neurotransmission in the autonomic and somatic nervous systems. The parasympathetic nervous system consists of cranial and sacral nerves with long preganglionic and short postganglionic fibers. The sympathetic nervous…

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Drug Development and Safety

Jan 1, 2017 by in PHARMACY Comments Off on Drug Development and Safety

Figure 4–1 Steps in the process of drug development in the United States. IND = investigational new drug; NDA = new drug application. Discovery and Characterization New drug compounds are…

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Acetylcholine Receptor Antagonists

Jan 1, 2017 by in PHARMACY Comments Off on Acetylcholine Receptor Antagonists

Figure 7-1 Dose-dependent effects of atropine. Low doses of atropine inhibit salivation and sweating, and the magnitude of these effects increases as the dosage increases. Higher doses produce tachycardia, urinary…

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Introduction to Pharmacology

Jan 1, 2017 by in PHARMACY Comments Off on Introduction to Pharmacology

Figure 1–1 Relationship between pharmacokinetics and pharmacodynamics. Toxicology Toxicology is the study of poisons and organ toxicity. It focuses on the harmful effects of drugs and other chemicals, and on…

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