Inherited Disorders of Amino Acid Metabolism in Adults
Molecular Defects More than 90% of patients clinically classified as having MFS by the “Ghent criteria” have a mutation in the gene for fibrillin-1 (FBN1). Mutations in the same gene are…
Chagas Disease and African Trypanosomiasis
247 Amebiasis and Infection with Free-Living Amebas Rosa M. Andrade, Sharon L. Reed AMEBIASIS DEFINITION Amebiasis is an infection with the intestinal protozoan Entamoeba histolytica. About 90% of infections are…
Pneumocystis Infections
236 Histoplasmosis Chadi A. Hage, L. Joseph Wheat ETIOLOGY Histoplasma capsulatum, a thermal dimorphic fungus, is the etiologic agent of histoplasmosis. In most endemic areas, H. capsulatum var. capsulatum is…
The Bradyarrhythmias: Disorders of the Sinoatrial Node
274 The Bradyarrhythmias: Disorders of the Sinoatrial Node David D. Spragg, Gordon F. Tomaselli Electrical activation of the heart normally originates in the sinoatrial (SA) node, the predominant pacemaker. Other…
Nausea, Vomiting, and Indigestion
FIGURE 44-3 Acute epiglottitis. In this lateral soft tissue radiograph of the neck, the arrow indicates the enlarged edematous epiglottis (the “thumbprint sign”). TREATMENTEPIGLOTTITIS Security of the airway is always of…
Shigellosis
Morganella and Providencia may be extensively resistant to antibiotics. Most isolates are resistant to ampicillin, first-generation cephalosporins, nitrofurantoin, fosfomycin, tigecycline, and the polymyxins; 40% are resistant to fluoroquinolones. Morganella and…
Infections Due to Mixed Anaerobic Organisms
Tularemia is a zoonosis caused by Francisella tularensis. Humans of any age, sex, or race are universally susceptible to this systemic infection. Tularemia is primarily a disease of wild animals…
Cryptococcosis
236 Histoplasmosis Chadi A. Hage, L. Joseph Wheat ETIOLOGY Histoplasma capsulatum, a thermal dimorphic fungus, is the etiologic agent of histoplasmosis. In most endemic areas, H. capsulatum var. capsulatum is…
Dizziness and Vertigo
PYROGENS The term pyrogen (Greek pyro, “fire”) is used to describe any substance that causes fever. Exogenous pyrogens are derived from outside the patient; most are microbial products, microbial toxins,…
Atlas of Blood Smears of Malaria and Babesiosis
247 Amebiasis and Infection with Free-Living Amebas Rosa M. Andrade, Sharon L. Reed AMEBIASIS DEFINITION Amebiasis is an infection with the intestinal protozoan Entamoeba histolytica. About 90% of infections are…
