Trichofolliculoma
Trichofolliculoma Steven D. Billings, MD Key Facts Clinical Issues Usually presents on the face Benign hamartomatous lesion Face is most common location Microscopic Pathology Cystic tumor that communicates to overlying…
Protocol for Specimens of Squamous Cell Carcinoma of the Skin
Protocol for Specimens of Squamous Cell Carcinoma of the Skin David Cassarino, MD, PhD Squamous Cell Carcinoma of the Skin Biopsy, Excision, Reexcision, Lymphadenectomy Procedure ____ Biopsy, punch ____ Biopsy,…
Basal Cell Carcinoma
Basal Cell Carcinoma David Cassarino, MD, PhD Key Facts Terminology Low-grade malignancy of basal keratinocytes Etiology/Pathogenesis Related to sun exposure, radiation, immunosuppression May be derived from follicular stem cells Clinical…
Squamomelanocytic Tumor
Squamomelanocytic Tumor Christine J. Ko, MD Key Facts Terminology Admixed histopathologic features of both squamous cell carcinoma and malignant melanoma Original descriptions were of dermal-based tumors Clinical Issues Very rare…
Extramammary Paget Disease
Extramammary Paget Disease Elsa F. Velazquez, MD Key Facts Terminology Extramammary Paget disease (EMPD) Clinical Issues Erythematous patches or plaques with sharply defined borders May clinically mimic chronic eczema Microscopic…
Keratoacanthoma
Keratoacanthoma David Cassarino, MD, PhD Key Facts Terminology Keratoacanthoma (KA) Very well-differentiated SCC variant Etiology/Pathogenesis Similar to other forms of SCC, typically related to chronic solar (UV) damage Clinical Issues…
Lymphoepithelioma-like Carcinoma of the Skin
Lymphoepithelioma-like Carcinoma of the Skin David Cassarino, MD, PhD Key Facts Terminology Lymphoepithelioma-like carcinoma of the skin (LELCS) Poorly differentiated carcinoma, most likely variant of SCC, with prominent inflammatory infiltrate…
Squamous Cell Carcinoma (and Variants)
Squamous Cell Carcinoma (and Variants) David Cassarino, MD, PhD Key Facts Terminology Squamous cell carcinoma (SCC) Malignant epithelial tumor of squamous keratinocytes Etiology/Pathogenesis Most cases are related to UV radiation…
Verrucous Carcinoma (and Variants)
Verrucous Carcinoma (and Variants) Elsa F. Velazquez, MD Key Facts Clinical Issues Unicentric tumors are more frequent but multicentric ones may occur Some cases may be associated with viral warts…
Penile and Vulvar Intraepithelial Neoplasia
Penile and Vulvar Intraepithelial Neoplasia Elsa F. Velazquez, MD Key Facts Terminology Most warty, basaloid, and mixed VIN and PeIN replace 2/3 to entire thickness of epithelium (VIN III and…
