Primary Cutaneous Anaplastic Large Cell Lymphoma Aaron Auerbach, MD, PhD Key Facts Terminology One of the primary cutaneous CD30(+) T-cell lymphoproliferative disorders T-cell lymphoma of atypical, usually large CD30(+) cells,…
Conventional Blue Nevi Soheil Sam Dadras, MD, PhD Key Facts Terminology Benign melanocytic tumor composed of spindle-shaped and dendritic melanocytes and melanophages Clinical Issues Occurs in any age, in wide…
Lymphomatoid Papulosis Aaron Auerbach, MD, PhD Key Facts Terminology One of the CD30(+) T-cell lymphoproliferative disorders Recurrent lymphoproliferative cutaneous disorder Disorder with self-healing lesions that regress without treatment and have…
Leukemia Cutis Jeremy C. Wallentine, MD Key Facts Terminology Clinically identifiable cutaneous lesions secondary to cutaneous infiltration by neoplastic leukocytes (myeloid or lymphoid) Clinical Issues Presentation may precede (aleukemic LC),…
Aggressive Epidermotropic CD8+ Cytotoxic T-cell Lymphoma Aaron Auerbach, MD, PhD Key Facts Terminology Provisional diagnosis in the 2008 WHO, T-cell lymphoma consisting of CD8(+) cytotoxic αβ T cells in epidermis,…
Extramedullary Hematopoiesis Aaron Auerbach, MD, PhD Key Facts Terminology Formation of blood cells (erythroid cells, myeloid cells, megakaryocytes) outside bone marrow Most common in liver and spleen Hematopoiesis occurs in…
Systemic B-cell Lymphomas Involving the Skin Aaron Auerbach, MD, PhD Key Facts Terminology B-cell lymphoma that has spread to skin as a secondary site of disease Clinical Issues Systemic B-cell…
Lymphomatoid Granulomatosis Aaron Auerbach, MD, PhD Key Facts Terminology Extranodal angiocentric mature B-cell lymphoma that expresses Epstein-Barr virus (EBV) antigens Etiology/Pathogenesis Associated with immunodeficiency, ↑ involvement with allogeneic organ transplant,…
Cutaneous Marginal Zone B-cell Lymphoma Aaron Auerbach, MD, PhD Key Facts Terminology Non-Hodgkin small B-cell lymphoma of centrocytelike marginal zone cells Malignant B cells expanding marginal zones surrounding reactive follicles…
Adult T-cell Leukemia/Lymphoma Aaron Auerbach, MD, PhD Key Facts Etiology/Pathogenesis Long latency period between HTLV-1 infection and tumor development Small risk of ATLL in HTLV-1 infected people Tax viral oncoprotein…
