Cytomegalovirus Lymphadenitis Sa A. Wang, MD Key Facts Terminology Lymphadenitis caused by cytomegalovirus (CMV) infection Etiology/Pathogenesis Member of β-herpes viruses Causes cytopathic changes Lytic infection: Immediate-early, early, and late viral…
Toxoplasma Lymphadenitis Carlos E. Bueso-Ramos, MD, PhD Key Facts Etiology/Pathogenesis Toxoplasma gondii is parasitic protozoan Cat is definitive host for sexual stage of reproduction Oocysts containing trophozoites are generated that…
Cryptococcal Lymphadenitis Tariq Muzzafar, MBBS Key Facts Etiology/Pathogenesis Infection by Cryptococcus neoformans Most cases are associated with immunosuppression > 80% of cases associated with AIDS Microscopic Pathology Cryptococcus neoformans Single…
Bacillary Angiomatosis Roberto N. Miranda, MD Key Facts Terminology Nodules of small blood vessels resulting from infection by bacterium Bartonella henselae Etiology/Pathogenesis B. henselae and B. quintana are most common…
Histoplasma Lymphadenitis Tariq Muzzafar, MBBS Key Facts Etiology/Pathogenesis Histoplasma is endemic in Central America River valleys of midwestern and south-central USA Acute disseminated disease occurs in Immunocompromised subjects including AIDS…
Infectious Mononucleosis Pei Lin, MD Key Facts Etiology/Pathogenesis Epstein-Barr virus infection Clinical Issues Fever Pharyngitis Lymphadenopathy Microscopic Pathology Follicular and interfollicular hyperplasia Range of cells from small mature forms to…
Cat Scratch Disease Roberto N. Miranda, MD Key Facts Terminology Necrotizing inflammation caused by Bartonella henselae Etiology/Pathogenesis Bartonella henselae causes most cases of CSD 90% of patients report contact with…
Mycobacterium tuberculosis Lymphadenitis Tariq Muzzafar, MBBS Key Facts Clinical Issues High index of suspicion essential for diagnosis Definitive diagnosis by histology and culture of LN Molecular methods enable quicker identification…
Whipple Disease Sa A. Wang, MD Key Facts Etiology/Pathogenesis T. whipplei, gram-positive bacilli related to Actinomycetes Engulfed by tissue macrophages Systemic disease; affects many organ systems Exerts no visible cytotoxic…
Syphilitic Lymphadenitis Francisco Vega, MD, PhD Key Facts Terminology Syphilis: Chronic systemic infection caused by T. pallidum (Gram-negative spirochete) Clinical Issues Course of disease divided into 3 stages: Primary, secondary,…
