Glandular component may contain conventional ductal-type, clear cell, or signet ring cell components
Top Differential Diagnoses

Primary adenosquamous cell carcinoma in the tail of the pancreas shows a relatively well-demarcated, tan-white to yellow solid mass



Adenosquamous cell carcinoma of the pancreas demonstrates islands of malignant squamous cells with keratinization



Immunohistochemical stain for p63 shows nuclear staining in the squamous component

