4.  On Gomori trichrome staining, frozen sections of a muscle biopsy reveal numerous myofibers with a ragged profile and red subsarcolemmal deposits, as shown in this picture. This finding suggests which of the following muscle conditions?

  5.  A 4-year-old male presents with a history of progressive awkwardness and frequent falls. A clinical diagnosis of Duchenne muscular dystrophy can be confirmed or ruled out by:

  6.  A 60-year-old woman presents with progressive weakness and pain in the proximal muscles of both upper and lower extremities. Blood creatine kinase (CK) is very elevated. A biopsy of the quadriceps muscle reveals the changes depicted in this photomicrograph. Which of the following is the most likely diagnosis?

  7.  A 58-year-old man presents to medical attention with progressive distal weakness, particularly in the extensor muscles of the arms. His blood levels of creatine kinase are markedly increased. A muscle biopsy reveals the changes shown in this photomicrograph. Furthermore, many atrophic angular myofibers are seen. Which of the following is the most likely diagnosis?

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