Gynecomastoid Hyperplasia
Key Facts
Terminology
Gynecomastoid hyperplasia (GH)
Focal occurrence in a female of histologic changes identical to those seen in male gynecomastia
Clinical Issues
Usual clinical presentation is as palpable mass
GH is most commonly seen mammographically as area of asymmetric density but may form nodular mass
Microscopic Pathology
Ducts without lobule formation surrounded by periductal fibrosis and edema
Epithelial hyperplasia with formation of micropapillae
Top Differential Diagnoses
Low-grade micropapillary DCIS
Mammary hamartoma
Juvenile hypertrophy
 GH is characterized by end ducts without lobule formation  in an area of abundant fibrous stroma  in a female, associated with a mass. The borders may be circumscribed  or poorly defined. |
 On mammography, the most common finding associated with GH is an asymmetric density. Less commonly, GH forms a circumscribed mass  . |
TERMINOLOGY
Abbreviations
Gynecomastoid hyperplasia (GH)
Synonyms
Gynecomastia-like changes of female breast
Gynecomastia-like lesion of female breast
Definitions
Histologic changes in breast identical to those seen in male gynecomastia, usually forming palpable mass or asymmetric density by mammography
ETIOLOGY/PATHOGENESIS
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