Complementary and alternative medicines

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Complementary and alternative medicines





Introduction


Complementary/alternative medicine (CAM), originally referred to as ‘fringe’, ‘holistic’ or ‘natural’ medicine, was known as ‘alternative’ medicine in the 1970s and 1980s and, today, increasingly is called ‘integrated’ or ‘integrative’ medicine. Generally, it is referred to as complementary/alternative medicine, although the terms complementary medicine, alternative medicine and complementary therapies are used interchangeably. A definition of CAM, which has been adopted by the Cochrane Collaboration (see Ch. 20), is given in Box 24.1.



Historically, CAM was the main form of medicine available to the world’s populations. In many parts of the world it still is today. The term CAM originates from the fact that what we now know as conventional or pharmaceutical medicine, did not exist, hence the modern usage of the term. With the advent and expansion of discovery and production of mainly synthetic medicines by pharmaceutical companies, usage of mainly plant-based traditional medicines declined. These medicines are what we now refer to as CAM.


CAM is an umbrella term for a collection of different approaches to diagnosis and treatment. Over 50 diverse complementary therapies have been listed, some involving use of medicinal substances, while others use a range of therapeutic techniques. These range from homoeopathy (which involves the use of infinitely dilute preparations) to herbal medicine (the use of chemically rich plant material), and from acupuncture (which involves the insertion of needles into specific points on the body) to therapeutic touch and spiritual healing (including ‘distant’ healing, which does not require the laying on of hands). In addition, there are many forms of complementary therapies available, which use a variety of techniques, but no medicinal products, some use only medicinal products, and there are also those which involve both medicines and techniques.


Some of the most well known complementary therapies, including those using medicinal products, are described in Box 24.2.



Box 24.2   Descriptions of complementary therapies common in the UK


Complementary medicines can be conveniently divided into three categories, those using only medicinal substances, those using a therapy without medicinal substances, and those using both.



Therapies using medicinal substances




Flower remedies and essences


Developed in the UK by Dr Edward Bach, who believed that physical disease was the result of being at odds with one’s spiritual purpose, i.e. negative states of mind induce illness. His approach to health focused only on the mental state of the patient. He identified 38 negative psychological states of mind (e.g. jealousy, guilt, hopelessness) and developed a remedy designed to be used for each of these emotional states. The Bach collection comprises 39 remedies, 38 of which originate from flowers/trees, and ‘Rescue Remedy’, a combination of five of the other 38 remedies. Flower remedies are extremely dilute preparations, but are not homoeopathic remedies.


Many other countries have their own collection of flower remedies/essences based on native plants/trees, e.g. Australian Bush Essences.



Herbalism


Traditional herbalism had an historical basis, party based on the galenical model of the four ‘humours’ and the belief that an excess of any of the humours leads to disease. Today, treatment is aimed at ‘restoring balance’ and ‘strengthening bodily systems’. Herbalists aim to treat patients in a holistic way by selecting a herb or combination of herbs to treat a particular person and his/her unique set of symptoms. One of the principal tenets is that the whole plant extract, and not an isolated constituent, is responsible for the clinical effect. It is claimed that herbal constituents, and even combinations of herbs, work synergistically to achieve benefit and reduce the possibility of adverse effects.


Rational phytotherapy/phytomedicine (science-based herbal medicine) has an entirely different approach to that of traditional herbalism. It involves the use of specific plant (or plant part) extracts standardized to specific constituents (where possible) with documented pharmacological activity for the treatment of specific clinical conditions. In this regard, phytotherapy has a similar approach to that of conventional medicine.


This involves preparations made from plants or plant parts. In some instances (e.g. use by herbalists), a crude drug (e.g. dried leaf) is used. Manufactured products use extracts of plants or plant parts, formulated as, e.g. tablets, capsules, creams and tinctures. They may contain a single or multiple herbal ingredients, obviously including numerous single chemical entities.



Homoeopathy


The use of highly dilute, succussed substances to stimulate the body’s own healing activity (the ‘vital force’). One of the key principles is ‘like cures like’ – a substance which in large doses causes a set of symptoms in a healthy person can be used to treat such symptoms in an ill person, e.g. homoeopathic preparations of coffee (Coffea) are used to treat insomnia. Treatment is holistic – two patients with the same set of symptoms may be given different remedies depending on their personal characteristics, physical appearance, mental and emotional state, etc. Although there are several hypotheses, there is not yet a plausible explanation for the mechanism of action of homoeopathy. Furthermore, on balance, rigorous clinical trials do not show an effect for homoeopathy over that of placebo.


This uses highly dilute preparations which may be of plant, animal, mineral, insect, biological, drug/chemical or other origin. Formulations include tablets, pilules, creams/ointments, liquids and injections.




Traditional Chinese Medicine (TCM)


An ancient Chinese method of health care which coexists alongside orthodox medicine today. TCM includes a range of therapies, such as Chinese massage, but is best known for the practices of traditional Chinese acupuncture (see below) and traditional Chinese herbal medicine (CHM). The basic concepts of TCM (‘yin-yang’ and the ‘five elements’) apply to CHM. The fundamental principle of treatment is to restore ‘balance and harmony’. Medicinal substances are classified as having particular attributes, e.g. hot, cold, tonifying, moistening and it is the consideration and combining of these attributes during therapy that is thought to bring about balance to patterns of clinical dysfunction. For example, ‘cooling’ herbs would be used to treat a patient whose pattern of illness is described as ‘hot’. Usually, herbal formulae comprising around 4–12 different medicinal substances are used to treat specific clinical patterns. Substances used as part of traditional Chinese medicine may include animal as well as herbal material.



Therapies not using medicinal substances



Acupuncture


This involves insertion of needles into a specific point or set of points on the body for the treatment of specific conditions. Various forms exist, such as auriculoacupuncture (needling of specific points on the ear) and electroacupuncture (electrical stimulation of inserted needles). The two main types practised in the UK are described below.


Medical acupuncture: usually practised by doctors who have trained in acupuncture and who use the therapy alongside conventional medicine. Insertion of needles is given as far as possible according to the principles of neurophysiology and anatomy (i.e. directed at stimulating nerve endings).


Traditional Chinese acupuncture: part of the broader system of traditional Chinese medicine (TCM). Traditional Chinese acupuncturists aim to restore the balance of energy in the body by ‘unblocking meridians’ (pathways along which life energy is believed to flow) by inserting needles strategically in specific points along meridians.



Chiropractic


Chiropractors believe that misaligned or maladjusted vertebrae (‘subluxations’), caused by accidents, strains, poor posture, innate skeletal distortions, etc., affect the spine and surrounding muscles, nerves and ligaments. This is believed to result in local or radiating pain, affecting joint movement, and causing swelling or weakening of muscle groups, thereby contributing to the disease process. There is, as yet, no clear explanation from current knowledge of spinal mechanics and neurophysiology how this might happen.


Chiropractic diagnosis includes physical examination, palpation of the vertebral column, assessment of posture, etc. and often the use of X-rays to examine bone alignment and to detect conditions such as osteoporosis which would contraindicate manipulative treatment. The principal technique used in chiropractic is a series of short sharp thrusts aimed at restoring normal joint motion, correcting subluxations, improving posture and/or removing painful stimulation to the nerves. Generally, chiropractors manipulate the neck and spine.




Osteopathy


Osteopaths believe that a wide variety of disorders can be traced to disorders of the musculoskeletal system, particularly the spinal vertebrae, but also to dysfunction in certain muscle groups. Manipulative techniques are used to correct these joint and tissue disturbances to restore normal bodily function. Osteopaths use a detailed medical history, physical examination, assessment of posture, observation of patient movement, etc. and, occasionally, X-rays in diagnosis. Direct techniques (soft tissue and joint movement, and high-velocity thrusts) and indirect techniques (positioning-type techniques where the joints are moved without force) are used in treatment. Generally osteopaths use more rhythmical and gentler pressure on the whole body, including the spine, whereas chiropractors tend to use more sharp, short, thrusting pressure on the spine.




Therapies using both medicinal substances and other treatment



Anthroposophical medicine


A philosophical vision of health and disease based on the work of Rudolf Steiner who explored how man’s soul and spiritual nature relate to the health and function of the body. Steiner viewed each person as having four ‘bodies’ or ‘forces’: physical, etheric, astral, spiritual. Practitioners of anthroposophy aim to understand illness in terms of how these four elements interact; the aim of treatment is to stimulate the natural healing forces of the body. The anthroposophic approach is a holistic one; practitioners may use a range of therapies including diet, therapeutic movement (eurhythmy) and artistic therapies as well as anthroposophic medicines in an integrated therapeutic programme. The medicines are derived mainly from plant and mineral sources; many are combinations of herbal ingredients. Particular attention is paid to the source and methods of farming used in growing raw plant materials for preparing anthroposophic medicines (e.g. organic culture only).



Several complementary therapies, such as herbalism, homoeopathy, aromatherapy and others, involve the administration of remedies, often in recognizable pharmaceutical formulations, e.g. herbal medicines, homoeopathic remedies and essential oils. These are collectively referred to as complementary (or ‘alternative’) medicines. As well as being used by some CAM practitioners in their practice, these types of products are widely available for purchase for self-treatment. Many of these are administered or recommended after consultation with therapists with varying range of abilities and qualifications, or simply bought by patients believing that they will be beneficial. In the UK, patients, the public, the media and many other groups consider the use of herbal medicines (whether prescribed by a herbalist or purchased over the counter), to be part of CAM. However, there is a view that herbal medicinal products with documented pharmacological activity and clinical efficacy lie alongside conventional medicines. Indeed, some herbal medicines, such as senna preparations, are conventional medicines.


This chapter discusses CAM, mainly from a UK perspective. In particular, the extent of use, and regulatory aspects of CAM are considered, as well as issues of importance to pharmacy and pharmacists. There is a particular emphasis on complementary medicines, as these are widely available in pharmacies, and especially on ‘European’ herbal medicines, as these are among the most widely used ‘complementary medicines’ in the UK. Also, from a biomedical perspective, herbal medicines (rather than, e.g. homeopathy) are likely to have the greatest potential in terms of both benefits and risks.

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Jun 24, 2016 | Posted by in PHARMACY | Comments Off on Complementary and alternative medicines

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